Protein Alignment GstT3 and CLIC2

DIOPT Version :9

• Sequence 1: NP_001162808.1
• Gene: GstT3 / 33047
• FlyBaseID: FBgn0031117
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_001280.3
• Gene: CLIC2 / 1193
• HGNCID: 2063
• Length: 247
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 50/257 - (19%)
• Similarity: 88/257 - (34%)
• Gaps: 101/257 - (39%)

  Fly    33 SRQPTNLRMSAPIRYYYDLMSQPSRALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEINRFQRV 97
            :|:|..|:..||                    .:|.||      |...:.|..||.| |..|
Human    55 TRKPEELKDLAP--------------------GTNPPF------LVYNKELKTDFIK-IEEF--- 89

  Fly    98 PCIHDNGYKLAESVAILRYLSAKGKIPEHLYPKYFVDQSRVDEFLEWQHMSLRLTCAMYFR-TVW 161
                     |.:::|..||        .||.|||              ..|..:.|.::.: :.:
Human    90 ---------LEQTLAPPRY--------PHLSPKY--------------KESFDVGCNLFAKFSAY 123

  Fly   162 LEPLLTGRTPSEAK-------IETFR---------MQMERNLDVVEEVWLEGKDFLTGSSLTVAD 210
            ::     .|..||.       ::.|:         :..|.:.|..||..:..:.||.|..||:||
Human   124 IK-----NTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLTLAD 183

  Fly   211 IFAACEIEQTRMA-----DYDVRIKYPKIRAWL------KRVRQSC-------NPYYDVAHE 254
            .....::...::|     |:|:..::..:..:|      :....:|       |.|.:||.:
Human   184 CSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYANVAKQ 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	14/75 (19%)
		GstA	47..243	CDD:223698	40/223 (18%)
		GST_C_Theta	135..259	CDD:198292	26/155 (17%)
CLIC2	NP_001280.3	Required for insertion into the membrane. /evidence=ECO:0000250	1..96		16/79 (20%)
		N-terminal	1..94		16/77 (21%)
		O-ClC	12..245	CDD:129941	50/255 (20%)
		Joint loop	95..106		6/18 (33%)
		C-terminal	107..247		26/144 (18%)
		Foot loop	151..171		4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154388
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930