Protein Alignment CG1695 and MSB3

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_014106.1
• Gene: MSB3 / 855423
• SGDID: S000005237
• Length: 633
• Species: Saccharomyces cerevisiae
• Alignment Length: 544
• Identity: 101/544 - (18%)
• Similarity: 191/544 - (35%)
• Gaps: 173/544 - (31%)

  Fly   694 EQARLA-ANATSSSNPHQKLA-----------NGSQQLQLEHGNGEEDQENLVLDEGENDVFDDN 746
            :|.|.: .|.|..::|:::|.           |...::..:|.:.:   ..||     |..|..|
Yeast     4 DQQRFSLQNRTVLAHPYKRLGGAFTVKSPSVPNFHDKMHSDHSSSD---SALV-----NGSFRAN 60

  Fly   747 DFSDISDPGDLFDEPE-LGQEAEEQEQSNL----------EEEVFEKQEDEEDQEDHDQREMPRL 800
            |...:        ||. |||.:..:...||          |.:..|.::|:::..|:...::..:
Yeast    61 DHRSV--------EPSCLGQASPSEHDGNLSVIDLYGDEVESQRAEGEDDDDNNGDNGNEDLEEV 117

  Fly   801 -SEKLVLEFQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVG--- 861
             |:.|.| ..:.||.:.:.|:....|.|...|.:                   :.:.::..|
Yeast   118 HSDDLDL-VPDDDNRQRVELEGAASATSANSNGI-------------------NNTHFDRYGFKK 162

  Fly   862 -NEFLDMAEAKLEEEEPPGQLSKF---HSADDVRLDNQDEEESSQPATAVIITEAASLDALDDDP 922
             |.::..||           ..|:   :|...||..::.:          ::.|.:.|...||.|
Yeast   163 QNNYISEAE-----------YDKWWVEYSQYCVRRKHKWQ----------LLLEKSGLPVTDDSP 206

  Fly   923 TEEFTSRKTSLMSPLNEDITVVASLDAL------QEPKSACVSPASSNGGVYSVELL-------- 973
            : .|.|:...|...:.:.|......:|.      ||       ..:.|.|||| :||
Yeast   207 S-RFPSKSERLKRYVRKGIPAEWRGNAWWHFARGQE-------KLNKNKGVYS-QLLRKMKQIKK 262

  Fly   974 ----EQFGLNLHRIEKDVQRCDRNYWYFANENLDK--------LRNVISTYVWEHLDVGYMQGMC 1026
                |:...:|..||:|:.|...:..:|.:...:|        ||.|:..:...:..:||.|.|
Yeast   263 QNPNEKQVQDLDIIERDLNRTFPDNIHFQSSLHNKEGPPIIKSLRRVLVAFSLYNPKIGYCQSM- 326

  Fly  1027 DLVAPLLVIFDDESLSYSCFCKLMERMIE----------NFPSGGAM------------------ 1063
            :.:|.||::|.||..::.....:..|.:.          |...|..|
Yeast   327 NFLAGLLLLFLDEERAFWMLVIITSRYLPGVHNINLEGVNIDQGVLMLCVKEYIPEVWSYIKPSI 391

  Fly  1064 DMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYR----------WFLLDFKRELVYDDVFATW 1118
            |.|..|.::........::::..:.       |.||          ||:..|...:..:.....|
Yeast   392 DHHQKNNKTFSPSNKKVLFNMQKNE-------FLYRLPPITLCTASWFMSCFVGVVPIETTLRIW 449

  Fly  1119 EVIWAAKHIASGHFVLFLALALLE 1142
            :.::    ....||:..::||:|:
Yeast   450 DCLF----YEESHFLFKVSLAVLK 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431
		TBC	947..1124	CDD:214540	45/240 (19%)
MSB3	NP_014106.1	COG5210	15..540	CDD:227535	97/533 (18%)