DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1695 and AT5G53570

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_001154777.1	Gene:	AT5G53570 / 835439	AraportID:	AT5G53570	Length:	577	Species:	Arabidopsis thaliana

Alignment Length:	734	Identity:	158/734 - (21%)
Similarity:	254/734 - (34%)	Gaps:	244/734 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   505 RRKHLGSCSTTGSSDC---SSKSLSIDQSSCETPLIQASQSTSIELVCSTMRRQIISRAFYGWLA 566
            ||.:..:.|...||..   ||.|.|:..||..:|....|.|.|         ....|.:...|:
plant    32 RRSYTSTSSGNSSSSSSLPSSSSSSLPSSSSSSPPSSNSNSYS---------NSNSSSSSSSWI- 86

  Fly   567 YCRHLSTVR--THLSGLVNGRIMPDLAADEE--------------GLTRGKWLAMH--EDGVVTG 613
               ||.:|.  .:||.       |......:              .||..:|.::.  |..:..|
plant    87 ---HLRSVLFVANLSS-------PSSVTSSDRRRKSPWSRRKRKWALTPHQWRSLFTPEGKLRDG 141

  Fly   614 DLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEAIVRQ 678
            .:...:.|...||:|.:|.|||.:|||.||..||.|||                     ||:..|
plant   142 GVGFLKKVRSRGVDPSIRAEVWLFLLGVYDLNSTSEER---------------------EAVKTQ 185

  Fly   679 REKEKTALAVAKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGEEDQ-ENLVLDEGENDV 742
            :.||                          ::||....|.| |:.|||..|. |.|..||..:..
plant   186 KRKE--------------------------YEKLQRRCQML-LKCGNGSTDNLEELPSDEANSQC 223

  Fly   743 FDDNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLE 807
            ....|...|:.|                                             ::.:.|:.
plant   224 VRFVDDYKITGP---------------------------------------------MTSQDVVS 243

  Fly   808 FQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAKL 872
            ..|.|:.:         .||..:|:         ::|:||               .|....|.|.
plant   244 ALNTDSSD---------TDSCEDNE---------DVLLLS---------------SFAHSDEKKP 275

  Fly   873 EEEEPPGQLSKFHSADDVRLDNQDEEESSQPATAVIITEAASLDALDDDPTEEFTSRKTSLMSPL 937
            ||:..               :|..||.||      ::..|||...::....|:|::.:.
plant   276 EEDNS---------------NNNSEENSS------LLVAAASEVQVEVAVHEDFSTWQR------ 313

  Fly   938 NEDITVVASLDALQ--------EPKSACVSPASSNGGVYSVELLEQFGLNLHRIEKDVQRCDRNY 994
                  :..||||:        .|.|..::.:.:.      .|.|..||      ||....:...
plant   314 ------IIRLDALRADSEWANYSPYSTAITESKAR------RLAESVGL------KDYDHLESCR 360

  Fly   995 WYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPS 1059
            .|.|    .:|..::..|.....::||.|||.||::|:|.:..::..::.||...|::...||..
plant   361 LYHA----ARLVAILEAYAMYDPEIGYCQGMSDLLSPILAVISEDHEAFWCFVGFMKKARHNFRL 421

  Fly  1060 GGA-MDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWA 1123
            ..| :....:.:..:|:..||::|..:: |.......|.||..|:.|:|||.::.....|||:||
plant   422 DEAGIQRQLSIVSKIIKNKDSQLYKHLE-NLQAEDCSFVYRMVLVMFRRELSFEQTLCLWEVMWA 485

  Fly  1124 AK-HIASG----------------HFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNA 1171
            .: .|.:|                ..:|..|:|.|...|.:|:.......::::..|.||.:.|.
plant   486 DQAAIRAGVGKSPWSRIRQQAPPTDDLLLYAIAALVLRRKLIIQKYSSMDEIVEECNSMAGQLNV 550

  Fly  1172 QSILQLSRSLVLQLQTIIE 1190
            ..:|..:..||:.|...||
plant   551 WKLLDDAHHLVVTLHDKIE 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	9/64 (14%)
		TBC	947..1124	CDD:214540	48/185 (26%)
AT5G53570	NP_001154777.1	TBC	<370..486	CDD:214540	33/116 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810