DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1695 and AT5G52580

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_001190524.1	Gene:	AT5G52580 / 835335	AraportID:	AT5G52580	Length:	690	Species:	Arabidopsis thaliana

Alignment Length:	936	Identity:	198/936 - (21%)
Similarity:	327/936 - (34%)	Gaps:	312/936 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   276 LHTSSEDTSSGSFKACSPASV-----AKDYVESLHQNSRTTLLYGKNNVLVLPKD-VSEPMPGYL 334
            |...|:|....:.:....||:     .|..::|.|:::  .|:|.|:||.:.|.. .||.:.|.|
plant     8 LQDLSDDADYAASQQQGSASMMRSDSGKRSLQSEHEDA--VLIYLKDNVAIHPTQFASERISGRL 70

  Fly   335 SLHQSIQSLTIKWTPNQLMNGYNDGDGGDKSFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILV 399
            .|.:....|.:.|.|.:...........|:|.|...|  :...|:..:..|....|  ...:|:|
plant    71 KLTKQDSVLFLSWIPYKGQTSNAKLSEKDRSLYTITA--VPFTEVRSIRRHTPALG--WQYVIVV 131

  Fly   400 GQDGVQRPPIHFPEGGHLQAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHILPSVME 464
            ...|:..||::|..|| ::.||:                              .|::|:.
plant   132 LSSGLAFPPLYFYNGG-VREFLA------------------------------MVKQHVF----- 160

  Fly   465 AGGSVTDETPIDYVFRVVSKCQHEEFLASHPILELGRSSPRRKHLGSCSTTGSSDCSSKSLSIDQ 529
            ...|..|:.    || :|:..|                ||.::.|.|...       ..||.:..
plant   161 LARSSEDQN----VF-IVNDFQ----------------SPLQRTLSSLEL-------PSSLPVAS 197

  Fly   530 SSCETPLIQASQSTSIELVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRIMPDLAADE 594
            .....||...|.|       ...||                       .|..|..|:.   :..:
plant   198 GQSVYPLDGGSSS-------ENQRR-----------------------TSSDVGNRVS---SVSQ 229

  Fly   595 EGLTRGKWLAMHEDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCK 659
            .|..:.|   .|:.   |.||.::.|..|..|....|.........:..|||..   |:.:....
plant   230 SGFRKQK---SHDP---TRDLSIHLLEKFSLVTKFARDTTTQLFSENNGFGSID---KRWNNQPV 285

  Fly   660 HYYETTMSEWLAVEAIVRQREKEKTALAVAKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHG 724
            |.|.                                              :||:|
plant   286 HSYP----------------------------------------------EKLSN---------- 294

  Fly   725 NGEEDQENLVLDEGENDVFDDNDFSDISDPGD--LFD----------EPELGQEAEEQEQSNLEE 777
            ..||....:.....|||:..|::.|.|..|.|  .||          :|.:|.:
plant   295 IAEEKHHEIRHSYSENDLLKDDEISYIDVPADPLEFDKLSLMWGKPRQPPMGHK----------- 348

  Fly   778 EVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPLRLQENCFADSETENDLGLGLDSSGN 842
               |::.|              :|..:                 .|...:|....|   |||.|.
plant   349 ---ERRND--------------ISPSI-----------------KCRISTEYFTAL---LDSEGR 376

  Fly   843 ILMLSIKSSPSTSSYETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQDEEESSQPATAV 907
            ::       .|.:..|.|   |....|.:|..|..|..|. :::.|....:.       :...:|
plant   377 VV-------ESKALRERV---FYGGIEHQLRREVWPFLLG-YYAYDSTYAER-------EYLRSV 423

  Fly   908 IITEAASL----DALDDDPTEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVSPASSNGGVY 968
            ...|.|:|    .::..:..:.||..:
plant   424 KRMEYATLKQQWQSISPEQAKRFTKYR-------------------------------------- 450

  Fly   969 SVELLEQFGLNLHRIEKDVQRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVGYMQGMCDLVA 1030
                 |:.||    |:|||.|.||.:.|:.   |.:::.:|:::.||.:.:.|:||.|||.|.::
plant   451 -----ERKGL----IDKDVVRTDRAFEYYEGDDNLHVNSMRDILLTYSFYNFDLGYCQGMSDYLS 506

  Fly  1031 PLLVIFDDESLSYSCFCKLMERMIENF--PSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTH 1093
            |:|.:.:|||.|:.||..||||:..||  ...|.....|| :..|:::|||.:::....| |..:
plant   507 PILFVMEDESESFWCFVALMERLGPNFNRDQNGMHTQLFA-LSKLVELLDSPLHNYFKEN-DCLN 569

  Fly  1094 FYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDV 1158
            ::||:||.|:.||||..|:.....|||:|.  |..|.||.|::.:|:|:..|..|:...|||..:
plant   570 YFFCFRWILIQFKREFEYEKTMQLWEVMWT--HYLSEHFHLYVCVAVLKRCRSKIMGEQMDFDTL 632

  Fly  1159 IKFFNEMAERHNAQSILQLSRSLVLQ 1184
            :||.||::...:..|.::.:.:|.::
plant   633 LKFINELSGHIDLDSTVRDAEALCIE 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431	38/175 (22%)
		SRP68-RBD	<648..>713	CDD:304552	4/64 (6%)
		TBC	947..1124	CDD:214540	59/181 (33%)
AT5G52580	NP_001190524.1	DUF3548	47..183	CDD:192931	41/196 (21%)
AT5G52580	NP_001190524.1	TBC	388..623	CDD:214540	80/293 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I1101
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960