DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1695 and AT3G49350

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_190504.2	Gene:	AT3G49350 / 824097	AraportID:	AT3G49350	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	723	Identity:	164/723 - (22%)
Similarity:	259/723 - (35%)	Gaps:	226/723 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   507 KHLGSCSTTGSSDCSSKSLSIDQSSCETPLIQASQSTSIELVCSTMRRQIISRAFYGWLAYCRHL 571
            |.|....||.||...|..||...||        |.|:|                   |:.....|
plant     2 KALRRIQTTSSSSNPSSPLSSPPSS--------SSSSS-------------------WIQIRSAL 39

  Fly   572 STVRTHLSGLVNGRIMPDLAADEEGLTRGKWLAMHE-------DG-VVTGDLELYRLVYFGGVEP 628
            ..|.:......:.|  |.|.:......|.:.|...:       || :..|.::|.:.|...|:||
plant    40 FVVASSSPASCSDR--PRLKSPWSRRKRKRPLRPQQWKRFFTPDGRLRNGGVDLLKKVRSRGIEP 102

  Fly   629 ELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAKLSA 693
            .:|.||||:|||.|.|.|:.|||                      ..:|.|.:::    ..:|..
plant   103 SIRLEVWPFLLGLYGFNSSKEER----------------------VTIRNRRRKE----YERLRR 141

  Fly   694 EQARLAANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGDLF 758
            :..||..:    :|..:||.|||:.:|                                   |.:
plant   142 QCKRLQKH----NNGTRKLYNGSETIQ-----------------------------------DEY 167

  Fly   759 DEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPLRLQENC 823
            |.|.:     :...|:..:||...:|.....||..: ::..:||
plant   168 DWPRV-----QDTDSSCSDEVVSARESLSSDEDITE-DIGYMSE--------------------- 205

  Fly   824 FADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAKLEEEEPPGQLSKFHSAD 888
             .....|.|.|   .||..|...:|.:..|.||            ::...:|....|:.:..:..
plant   206 -VSCTVERDDG---SSSRRITNATISTLNSESS------------DSDSSDESEVVQVFQSSATP 254

  Fly   889 DVRLDNQDEEESSQPATAVI-------IT--EAASLDALDDDPTEEFTSRKTSLMSPLNEDITVV 944
            ||        .|:.||::.|       :|  ....|||:..|  .|:||...| .:.::||
plant   255 DV--------NSTYPASSSIPRTEEDFVTWQRIIRLDAVRAD--SEWTSYSPS-QAVISED---- 304

  Fly   945 ASLDALQEPKSACVSPASSNGGVYSVELLEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVI 1009
                      .||             ...|..||      ||....: .|..|   ...:|..|:
plant   305 ----------RAC-------------RAAEAVGL------KDYNHLE-PYKIF---QAARLVAVL 336

  Fly  1010 STYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRS-L 1073
            ..|.....|:||.|||.||::|:|.:..|:...:.||...|::...||...........|:.| :
plant   337 EAYALYDPDIGYCQGMSDLLSPILSVIPDDHEVFWCFVGFMKKARHNFRLDEVGIRRQLNIVSKI 401

  Fly  1074 IQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAK-HIASG------- 1130
            |:..||::|..::.. .....:|.||..::.|:|||..|.....|||:||.: .|.:|
plant   402 IKSKDSQLYRHLEKL-QAEDCFFVYRMVVVMFRRELTLDQTLCLWEVMWADQAAIRAGMGKSAWS 465

  Fly  1131 ----------HFVLF-LALALLETYRDII-LSNSMDFTDVIKFFNEMAERHNAQSILQLSRSLVL 1183
                      ..||: :|.::|:..:.|| ..||||  ::::....||.:.:...:|..:..||:
plant   466 RIRQRAPPTDDLVLYAIAASVLQRRKRIIERYNSMD--EILRECQSMAGQLDVWKLLDDAHDLVV 528

  Fly  1184 QLQTIIEN 1191
            .|.|.||:
plant   529 TLHTKIEH 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	10/64 (16%)
		TBC	947..1124	CDD:214540	46/177 (26%)
AT3G49350	NP_190504.2	TBC	<335..451	CDD:214540	36/116 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810