Protein Alignment CG1695 and Tbc1d8

DIOPT Version :9

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_006244913.1
• Gene: Tbc1d8 / 680133
• RGDID: 1595491
• Length: 1150
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 104/601 - (17%)
• Similarity: 200/601 - (33%)
• Gaps: 197/601 - (32%)

  Fly   745 DNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREM-PRLSEKLVLEF 808
            :.|||...:..::|...|  |.|:...:..|:.|||:...|.::.....:|:: .|...:....|
  Rat   243 ERDFSTFLNLDEVFKIME--QLADVTLRRLLDNEVFDLDPDLQEPSQITKRDLEARAQNEFFRAF 305

  Fly   809 QNIDNMEPLRLQEN-----------------------CFADSETENDLGLGLDSSGNILM----- 845
            ..:...|.|....:                       |||..|         |...::::
  Rat   306 FRLPRKEKLHAVVDCSLWTPFSRCHTAGRIFSSDSYICFASRE---------DGCCHVVLPLREV 361

  Fly   846 LSIKSSPSTSSY---------ETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLD-NQDEEES 900
            :||:....||..         ..:..:|:::.:.:...|....:|.:.|:...|..: :..:::.
  Rat   362 VSIEKMEDTSLLPNPIIVSIRSKMAFQFIELKDRENLVEGLLLRLKQVHANHPVHYETSPSDDDM 426

  Fly   901 SQP---ATAVIITEAASLDALDDDPTEEFTSRKTSLMSPLNEDITVVASLDALQEP--------- 953
            :.|   :|::...:...|:.:....:||....|:.|..|  |.:|.|......|.|
  Rat   427 ASPVFYSTSICTDKFGDLEMVSSQSSEEREKEKSPLPHP--EPLTAVFQQSGSQSPDSRLSREQI 489

  Fly   954 -------------KSAC------------------------------VSPASSNGGVYSVELLEQ 975
                         ::.|                              |:..:|:.|.|. .|:||
  Rat   490 KISLWNDHFAEYGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGYYG-NLVEQ 553

  Fly   976 -FG---LNLHRIEKDVQRCDRNYWYFANE-NLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVI 1035
             .|   |....||:|:.|....:..|.|| .:..||.|::.|...:..:||.|.| :::..:|::
  Rat   554 SLGRCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQSM-NILTSVLLL 617

  Fly  1036 FDDESLSYSCFCKLMERMIENFPS----GGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHF-Y 1095
            :..|..::.....:.|||:.::.:    |..:|.....     :::...:.:|.:...|.:.. .
  Rat   618 YAKEEEAFWLLVAVCERMLPDYFNHRVIGAQVDQSVFE-----ELIKEHLPELAEHMSDLSALAS 677

  Fly  1096 FCYRWFLLDFKREL------------VYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRD-- 1146
            ....|||..|...:            .||.:.|.::                |.||:||...:
  Rat   678 ISLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQ----------------LGLAVLEANAEEL 726

  Fly  1147 ----------IILSNSMD---------------------------FTDVIKFFNEMAERHNAQSI 1174
                      :|||..:|                           .||:.....:..|:...||:
  Rat   727 CSSKDDGQALMILSRFLDHIKNEDSPGPPIGSHHAFFSDDQEPCPVTDIADLIRDSYEKFGNQSV 791

  Fly  1175 LQLS------RSLVLQ 1184
            .|:.      |..|||
  Rat   792 EQIEHLRCKHRIRVLQ 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552
		TBC	947..1124	CDD:214540	43/250 (17%)
Tbc1d8	XP_006244913.1	PH-GRAM1_TBC1D8	171..269	CDD:270156	7/27 (26%)
		PH-GRAM2_TBC1D8	311..406	CDD:270160	13/103 (13%)
		TBC	520..726	CDD:214540	45/228 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900