Protein Alignment CG1695 and Tbc1d15

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001414153.1
• Gene: Tbc1d15 / 66687
• MGIID: 1913937
• Length: 688
• Species: Mus musculus
• Alignment Length: 698
• Identity: 160/698 - (22%)
• Similarity: 264/698 - (37%)
• Gaps: 178/698 - (25%)

  Fly   579 SGLVNGRIMPDLAADEEGL----TRGKWLAMHEDGVVTGDLELYRLVYFGGVEPELRKEV----- 634
            :|:|:|:|:    .::||:    :.||  |..:|.:::|.|.:            |.|:.
Mouse     4 AGVVSGKII----YEQEGVYIHSSCGK--ANDQDSLISGILRV------------LEKDAEVIVD 50

  Fly   635 WPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAKLSAEQAR-- 697
            |..|....|..|.         .|.....:::.||       .|..||:......:.|:.:|.
Mouse    51 WRPLDDALDSSSI---------LCAGKDSSSVVEW-------TQAPKERAHRGSDQQSSYEAEWD 99

  Fly   698 LAANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGD------ 756
            :....:....||   .||...   .|.||:.....|         |...|...:....:
Mouse   100 MVTTVSFKKKPH---TNGDAP---GHRNGKSKWSFL---------FSLADLKSVKQSKEGMGWSY 149

  Fly   757 ----LFDEPELGQEAEEQEQSNLEEEVFEKQ----EDEEDQEDHDQREMPRLSEKLVLEFQNIDN 813
                |.|:..|......|..|.|..|..||.    |..:|            |..|::..||
Mouse   150 LVFCLKDDVMLPALHFHQGDSKLLIESLEKYVVLCESPQD------------SRTLLVNCQN--- 199

  Fly   814 MEPLRLQENCFADSETENDLGL---GLDSSGNILML-----SIKSSPSTSS---YETVGNEFLDM 867
                :.....|.:...|...||   ||.....:|..     .||..|.|::   :..|.|...|.
Mouse   200 ----KSLSQSFENLLDEPAYGLIQAGLLDRRKLLWAIHHWRKIKKDPYTATMVGFSKVTNYIFDS 260

  Fly   868 AEAK--LEEEEPPGQLSKFHSADDVRLD-NQDEEESSQPATAVIITEAASLDALDDDPTEEFTSR 929
            ....  ...:.||.:::.|.|.....|. ||.||...:..|.:.:.|...:...:....||:
Mouse   261 LRGSDPSTHQRPPSEMADFLSDAIPGLKINQQEEPGFEVITRIDLGERPVVQRREPVSLEEW--- 322

  Fly   930 KTSLMSPLNEDITVVASLDALQEPKSACVSPASSNGGV-YSVE------LL-------------- 973
                    |:.:.....|.|::..|....     .||: :|:.      ||
Mouse   323 --------NKSLDPEGRLVAVESMKQKIF-----RGGLSHSLRKQAWKFLLGYFPWDSTKEERTQ 374

  Fly   974 -------EQFGLNLH--------------------RIEKDVQRCDR-NYWYFANEN--LDKLRNV 1008
                   |.|.:.|.                    .|||||.|.|| |.:|...:|  |..|.::
Mouse   375 LQKQKTDEYFRMKLQWKSVSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDI 439

  Fly  1009 ISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSG-GAMDMHFANMRS 1072
            :.||.....|:||:|||.||::|||.:.::|..::.||...|::|.:||... ..|......:.:
Mouse   440 LMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLST 504

  Fly  1073 LIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLA 1137
            |:::|||.....::|. |..:.|||:||.|:.||||..:.|:...|||:|.  .:...:|.|.|.
Mouse   505 LLRLLDSGFCSYLESQ-DSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWT--ELPCKNFHLLLC 566

  Fly  1138 LALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSILQLSRSLVLQL 1185
            .|:||:.:..|::....|.:::|..||::.:.:.:.||..:.::.||:
Mouse   567 CAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAEAISLQM 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431
		TBC	947..1124	CDD:214540	66/228 (29%)
Tbc1d15	NP_001414153.1	PH_RBD	10..211	CDD:432305	49/268 (18%)
		TBC	343..578	CDD:214540	69/242 (29%)