DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1695 and rabgap1l2

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	XP_694092.1	Gene:	rabgap1l2 / 565728	ZFINID:	ZDB-GENE-070912-414	Length:	320	Species:	Danio rerio

Alignment Length:	313	Identity:	61/313 - (19%)
Similarity:	119/313 - (38%)	Gaps:	79/313 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   675 IVRQREKEK--TALAVAKL-----SAEQARLAANATSSSNPHQKLANGSQQLQ-----LEHGNGE 727
            |:.|..:|:  .:|.|..|     .:::.:|..|.....:|..|....:::||     ||..|.:
Zfish    15 IIDQMSEEEILASLVVESLPKQVVPSKKQKLRDNQEQPEDPLDKYERENRKLQETSLRLEQENDD 79

  Fly   728 EDQENL--------VLDEGENDVFDDNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQE 784
            ..|:.:        .||:.|:.|  |....::|....|....|..:..:|:|.|.| :|:|.|:.
Zfish    80 LAQKLVTSKIALRNALDQTEDQV--DELTKELSKVKQLLVVTEEEKRGKEEEASQL-KEMFRKEL 141

  Fly   785 DEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPLRLQENCFADSETENDLGL-------------- 835
            |:.:.:       .:.|..::.:::.|.:....:|:..   ..|.:.:|..
Zfish   142 DKAESD-------IKRSNSIIADYKQICSQLNTKLENQ---KEEADKNLAFIKSKLQECERCSRI 196

  Fly   836 -----GLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQ 895
                 .::|.......|.:....||..|.|.....::|:.||:..|...::.:        |::|
Zfish   197 FSVDGSIESCSESEDRSAQDEAKTSLREQVKELEKELAQTKLQMVESKCKIQE--------LEHQ 253

  Fly   896 DEEESSQPATAVIITEAASL------DALDDDPT----EEFTSRKTSLMSPLN 938
                     .||::||..:.      ..||...|    ::.:|:..|..||.|
Zfish   254 ---------KAVLMTELQAAKNTWLKKTLDSFKTAASGQQSSSQTDSAWSPNN 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	10/44 (23%)
		TBC	947..1124	CDD:214540
rabgap1l2	XP_694092.1	Smc	<56..>265	CDD:224117	44/238 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900