Protein Alignment CG1695 and tbc1d2

DIOPT Version :9

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_689604.6
• Gene: tbc1d2 / 561110
• ZFINID: ZDB-GENE-140106-100
• Length: 926
• Species: Danio rerio
• Alignment Length: 1002
• Identity: 183/1002 - (18%)
• Similarity: 323/1002 - (32%)
• Gaps: 363/1002 - (36%)

  Fly   348 TPNQL-MNGYNDGDGG-------------DKS---FYWSYALNINVDEIVYVHCHQNRGGDTGGT 395
            ||:.. :.||.:..||             :||   ||:..|.:||
Zfish    52 TPSSTKLCGYLNKQGGPLKTWKSRWFAYEEKSCQLFYYRMAHDIN-------------------- 96

  Fly   396 IILVGQDGVQRPPIHFPEGG-----HLQAFLSCLETGLLPHGQLDPPLW-------------SQR 442
              .:|:..:.|....:|..|     |:|   :...|.:|.....|..::             .|:
Zfish    97 --SLGKVDLTRATFSYPLRGEEGTFHIQ---TPERTVILKAANRDAQMYWLQQLQLKRAQFRDQQ 156

  Fly   443 GIGKLFPWPKSVR-----------RHILPSVMEAGGSVTDE----------TPIDYVFRVVSKCQ 486
            ...:..|.|.|:.           .:.||.|....|.|.:|          .|::...:
Zfish   157 AEHQSTPRPDSLTTESTPPANNCPANFLPMVKTPSGLVGEEAASLPAPGLNNPLNMSIK------ 215

  Fly   487 HEEFLASHPILELGRSSPRRKHLGSCSTTGSSDCSSKSLSIDQ-------SSCETPLIQASQSTS 544
                   ||::||      :..:.|.....|.:.......||.       :|.:|..:....:||
Zfish   216 -------HPLIEL------QNTMHSFRNRQSQEIRQSVFHIDDPGDTQKTTSPKTSTLVVPATTS 267

  Fly   545 IELVCSTMRRQIISRAFYGWLAYCR--HLSTVRTHLSGLVNGRIMPDLAADEEGLTRGKWLAMHE 607
            .:...|.::            |.|.  |    :.::|.:...|        :.|..|.::|.:.:
Zfish   268 YQAPESPVK------------AKCEDPH----QNNISTISQNR--------KSGKERSRFLDLKD 308

  Fly   608 DGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAV 672
                |..|:..:|..  ..|.:.:||:  .||.|    ...|..:.:..||        :::||.
Zfish   309 ----TSQLQHEKLSL--AEEVKAQKEL--VLLLH----KVLEAAQLEKRTC--------AQFLAA 353

  Fly   673 EA------IVRQREKEKTALAV--AKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGEED 729
            |.      ::|..|:....|.|  ..|..|...|..:.|.......:|.| |.||.|:.   .:.
Zfish   354 EGEQERMELLRHGERRAAELRVQLEALQQENENLRRDLTQRDEHVAELQN-SIQLLLQK---NQT 414

  Fly   730 QENLVLDEGENDVFDDNDFSDISDPGDLFDEPELGQEAEEQEQSN-LEEEVFEKQEDEEDQEDHD 793
            ::.::|...|                      :|....|:|:.:| ||.|.|.:...|.:|...|
Zfish   415 KQEVILKLSE----------------------KLTTCGEDQQYTNGLESETFRQMTMENEQLKDD 457

  Fly   794 QREMPRLSEKLVLEFQNIDNM----EPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPST 854
                        |:..||.|.    |..:|.......||.|..|.:      ...:|...:....
Zfish   458 ------------LKAYNIQNQYLNSEIYQLTMLWRKSSEREKSLIV------KCAVLEANNCQME 504

  Fly   855 SSYETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQDEEESSQPATAVIITEAASLDALD 919
            |.|..:..:..:..|...|:.|...::.|    |.|:.|               :..|..|:.:.
Zfish   505 SRYLGILQKLQESQELNPEQREAVNKMLK----DAVQAD---------------LNNAIKLNPIS 550

  Fly   920 DDPTEEFTSR-----KTSLMSPLNEDITVVASLDALQ--------------------------EP 953
            |  .:|:..|     |.       ||:.::|.:.||:                          .|
Zfish   551 D--YDEYGFRIAVDYKV-------EDLKLLAKIQALEFRSQNLLNQEECDGPLLARCAQLLFGRP 606

  Fly   954 KSACVSPASSNG----GV---YSV-----------------------ELLEQFGLNLHRIEKDVQ 988
            :....|.|...|    |:   |.|                       ||.|:...:.|.:.:.:|
Zfish   607 EGELTSSAEMKGLLRTGLPHEYRVRVWRFMIQTRTKSLRERHPDRYHELCEKSRSSPHLVPRQIQ 671

  Fly   989 RCDRNYWYFANEN--------LDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSC 1045
             .|.:....:|::        :.||..|:..:.|.:..:||:||:..|.|..|::..:|:.::.|
Zfish   672 -LDLDRTLTSNKHFSPPTSPLIQKLERVLQAFSWHNPTIGYVQGLNRLAAIALLVLQEEADAFWC 735

  Fly  1046 FCKLMER------------------------MIENFPSGGAMDMHFANMRSLIQILDSEMYDLMD 1086
            ...::|.                        |:|..|   .:..|...::..|.::..|
Zfish   736 LVVIVEHIMPPNYFTKDLVGCQADQRVLKDLMLEKLP---RLTAHLEALKVDISLITVE------ 791

  Fly  1087 SNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLETYRDIIL- 1149
                         |||:.|...|....:|..|:.:     :..|..|:| .||||.:...:.||
Zfish   792 -------------WFLVLFVESLPTRILFKVWDAL-----LYEGSKVIFRYALALFKYREEAILK 838

  Fly  1150 -SNSMDFTDVIKFF-NEMAERHNAQSI 1174
             .:|::....::.| |.:|:.....||
Zfish   839 IQDSVEMYQYLRIFPNTIADGRKLTSI 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431	33/192 (17%)
		SRP68-RBD	<648..>713	CDD:304552	14/72 (19%)
		TBC	947..1124	CDD:214540	43/264 (16%)
tbc1d2	XP_689604.6	PH	56..146	CDD:278594	20/114 (18%)
		PH_TBC1D2A	57..153	CDD:269966	20/120 (17%)
		TBC	621..837	CDD:214540	44/243 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900