| Sequence 1: | NP_728346.2 | Gene: | CG1695 / 33046 | FlyBaseID: | FBgn0031116 | Length: | 1192 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001254500.1 | Gene: | TBC1D2 / 55357 | HGNCID: | 18026 | Length: | 928 | Species: | Homo sapiens |
| Alignment Length: | 660 | Identity: | 133/660 - (20%) |
|---|---|---|---|
| Similarity: | 246/660 - (37%) | Gaps: | 199/660 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 646 STPEERKKQDETCKHYYE------TTMSEWLAVEAIVRQREKE-KTALAVAKL------SAEQAR 697
Fly 698 LAANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGDLFDEPE 762
Fly 763 LGQ--EAEEQEQSNL-------EEEVFEKQEDEE---DQEDHDQREMPRLSEKLVLEFQNIDNME 815
Fly 816 PLR-------------------------LQENCFADSE-----------TENDLGLGLDSSGNIL 844
Fly 845 MLSIKSSPSTSSY--------ETVGNEFLDMAE--AKLEEEE---PPGQ----------LSKFHS 886
Fly 887 ADDVRLDNQDEEESSQPATAVIITEAASLDALDDDPTEEFTSRKTSLMS------PLNE------ 939
Fly 940 DITVVASLDAL--------QEPK----------SACVSPASSNGGVYSVELLEQFGLNLH----R 982
Fly 983 IEKDVQRCDRNYWYF---ANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYS 1044
Fly 1045 CFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHF---YFCYRWFLLDFK 1106
Fly 1107 RELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLE-TYRDII-LSNSMDFTDVIKFFNEMAER 1168
Fly 1169 HNAQSILQLS 1178 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG1695 | NP_728346.2 | RUN | 63..237 | CDD:280855 | |
| PH_RUTBC | 310..485 | CDD:275431 | |||
| SRP68-RBD | <648..>713 | CDD:304552 | 16/77 (21%) | ||
| TBC | 947..1124 | CDD:214540 | 45/204 (22%) | ||
| TBC1D2 | NP_001254500.1 | Interaction with CADH1 | 1..169 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..39 | ||||
| PH_TBC1D2A | 47..147 | CDD:269966 | |||
| PH | 47..139 | CDD:278594 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 225..275 | ||||
| Interaction with RAC1. /evidence=ECO:0000269|PubMed:20116244 | 295..433 | 38/174 (22%) | |||
| TBC | 625..837 | CDD:214540 | 49/223 (22%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5210 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||