DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1695 and si:dkeyp-19e1.3

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	XP_005170766.1	Gene:	si:dkeyp-19e1.3 / 553000	ZFINID:	ZDB-GENE-081104-56	Length:	736	Species:	Danio rerio

Alignment Length:	226	Identity:	52/226 - (23%)
Similarity:	94/226 - (41%)	Gaps:	29/226 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   971 ELLEQFGLNLHRIEKDVQRCDRNYWYFANE---NLDKLRNVISTYVWEHLDVGYMQGMCDLVAPL 1032
            |..:::...:.:|:.||.|..||:..|...   ....|.:|::.|...:.:|.|.|||..:.|.|
Zfish   131 EQAKRYSTEIKQIDLDVNRTFRNHIMFMERFGVKQQALFHVLAAYSVYNTEVSYCQGMSQIAAIL 195

  Fly  1033 LVIFDDESLSYSCFCKLMER-------MIENFPSGGAMDMHFANMRS-LIQILDSEMYDLMDSNG 1089
            |:..::|...::....|..:       .|..||......:|...:.| |:..|.:.:.....|.|
Zfish   196 LMYMNEEDAFWALSQLLTNQKHAMHGFFIPGFPKLHRFQVHHDKILSKLLSKLRNHLEKEQMSTG 260

  Fly  1090 DYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVL-FLALALLETYRDIILSNSM 1153
            .||     .:|||..|.....:......|::     :|..|..|| .:|..||:.::..:|..|:
Zfish   261 IYT-----TKWFLQCFIDRTPFTLTLRLWDI-----YILEGEKVLTAMAYTLLKLHKKHLLKLSL 315

  Fly  1154 DFTDVIKFFNEMAERHNAQSILQLSRSLVLQ 1184
            :  |:.:|..|     ...|...:|..:|::
Zfish   316 E--DLREFLQE-----RTASSFNMSDDVVIE 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552
		TBC	947..1124	CDD:214540	37/163 (23%)
si:dkeyp-19e1.3	XP_005170766.1	TBC	96..301	CDD:214540	42/179 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810