Protein Alignment CG1695 and Sgsm1

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_006535185.1
• Gene: Sgsm1 / 52850
• MGIID: 107320
• Length: 1148
• Species: Mus musculus
• Alignment Length: 1260
• Identity: 574/1260 - (45%)
• Similarity: 740/1260 - (58%)
• Gaps: 209/1260 - (16%)

  Fly    25 AETELKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSHGLRRRALGLFKTSST 89
            ||.|.::||:.:|||||||:||||||:|:|||:||.:.|.|.|||||:.|||||||.|..:::..
Mouse     6 AEAETRQRLLRTVKKEVKQIMEEAVTRKFVHEDSSHIISFCAAVEACVLHGLRRRAAGFLRSNKI 70

  Fly    90 TALIQKIAKICPEADYVSRRLLELELAQES--HAVSGKRSSCSSDSIIK-PKLLSKGSGSSNSVT 151
            .||..|:.|..|.|:.:||::.|||...||  :.:.|.:     :::.| |||.:
Mouse    71 AALFMKVGKGFPPAEELSRKVQELEQLIESARNQIQGLQ-----ENVRKLPKLPN---------- 120

  Fly   152 TINTVTNGAGAGPGGGGGASAPLG-KYLWIRLALHEKRLAKIIEHLVSNANSYYDREALVADPDY 215
                               .:||. |:||||.||.|:.|.||:.:||.|::.||::|||:.||..
Mouse   121 -------------------LSPLAIKHLWIRTALFERVLDKIVHYLVENSSKYYEKEALLMDPVD 166

  Fly   216 GSILSSLLVGPCALEFTRAKTADHYWSDPCADELVQRHRISSGN-RTPPTTHRPIINFKRSLHTS 279
            |.||:||||||||||:|:.|||||:|:||.||||||||||.|.: |....|.||.:..::. |
Mouse   167 GPILASLLVGPCALEYTKMKTADHFWTDPSADELVQRHRIHSSHLRQDSPTKRPALCIQKR-H-- 228

  Fly   280 SEDTSSGSFKACSPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPMPGYLSLHQSIQSLT 344
                ||||... .|:..|:|||||||||||.|||||||||||.|:|..|.:||||||||:...:|
Mouse   229 ----SSGSMDD-RPSISARDYVESLHQNSRATLLYGKNNVLVQPRDDMEAVPGYLSLHQTADVMT 288

  Fly   345 IKWTPNQLMNGYNDGD-GGDKSFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILVGQDGVQRPP 408
            :|||||||||| :.|| ..:||.||.||:.|.::||||:||||.  .|:|||::||.|||:||||
Mouse   289 LKWTPNQLMNG-SVGDLDYEKSVYWDYAVTIRLEEIVYLHCHQQ--VDSGGTVVLVSQDGIQRPP 350

  Fly   409 IHFPEGGHLQAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHILPSVMEAGGSVTDET 473
            ..||:||||..||||||.|||||||||||||||||.||:|  ||..:|....|.........|:.
Mouse   351 FRFPKGGHLLQFLSCLENGLLPHGQLDPPLWSQRGKGKVF--PKLRKRSPQGSSESTSSDKEDDE 413

  Fly   474 PIDYVFRVVSKCQHEEFLA------SHPI--------LELGRS---------------------- 502
            ..|||||::......||:|      ..|:        |..|:|
Mouse   414 ATDYVFRIIYPGTQSEFVALDLMGSPRPVSIGPAWMMLAAGQSMLVVAKGLQWAQTRGCLTIPTR 478

  Fly   503 --------------------------SPRRKHLGSCSTTGSSDCSSKSLSIDQSSCETPLIQASQ 541
                                      |||:....|||.:||:|..|      .:.|.      .:
Mouse   479 SVKEQPPMPQDLMDVSMNNLPPLWQPSPRKSSCSSCSQSGSADGGS------TNGCN------HE 531

  Fly   542 STSIELVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRIM-PDLAADE-EGLTRGKWLA 604
            ...::|:|..|:.||:||||||||||||||||||||||.|||..|: |||..|. :|||...|..
Mouse   532 RAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLPCDAGQGLTASIWEK 596

  Fly   605 MHEDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEW 669
            ..:|.....:.||.||:|:|||:||:|:.|||:|||||.||.|..|||:.||.....|..|||||
Mouse   597 YIQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEMERKEVDEQIHACYAQTMSEW 661

  Fly   670 LAVEAIVRQREKEKTALAVAKLSAEQA-------RLAANATSSSNPHQKLANGSQQLQLEHGNGE 727
            |..||||||||:|..|.|:||.|:..:       .|..::|.|:...|..::|.|.|:|:..:..
Mouse   662 LGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLHRDSTISNESSQSCSSGRQNLRLQSDSSS 726

  Fly   728 EDQENLVLDEGENDVFD---DNDFSDI--SDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEE 787
            ..|....:||.|....:   :.....|  .:|.:....|:.|..:.....|.|.|. .|.....|
Mouse   727 STQVFESVDEVEQTEAEGRSEEKHPKIPNGNPANGTCSPDSGHPSSHNFSSGLSEH-SEPSLSTE 790

  Fly   788 DQEDHDQREMPRLSEKLVLEFQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSP 852
            |.....||.:|.:             ..|        .||..|:.                :||.
Mouse   791 DSVLDAQRSLPAV-------------FRP--------GDSSVEDG----------------QSSE 818

  Fly   853 STSSYETVGNEFL---DMAEAKLEEEEPPGQLSKFHSADDVRLDNQD-------EEESSQPATAV 907
            :|:|.:....|.|   |..|:.|...|...:......:.||.|..:|       ..|:.:|
Mouse   819 ATTSRDEAPREELAVQDSLESDLLANESLEEFMSIPGSLDVALPEKDGAVMDGWPGEADKP---- 879

  Fly   908 IITEAASLDALDDDPTEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVSPASSNGGVYSVEL 972
              :.|.|.|.|.::|..|      ||...|       ||| |:....:...||.||:|..||.||
Mouse   880 --SRADSEDNLSEEPEME------SLFPAL-------ASL-AVTSSANNEASPVSSSGVTYSPEL 928

  Fly   973 LEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFD 1037
            |:.:.:||||||||||||||:||||...||:||||::.:|:|:|:::||:||||||:||||||.|
Mouse   929 LDLYTVNLHRIEKDVQRCDRSYWYFTAANLEKLRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILD 993

  Fly  1038 DESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFL 1102
            ||:|::|||.:||:||.:|||.|||||.|||||||||||||||:::||..|||||||||||||||
Mouse   994 DEALAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRWFL 1058

  Fly  1103 LDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAE 1167
            |||||||||||||:.||.||||||::|.|:|||:||||:|.||||||.|:|||||:|||||||||
Mouse  1059 LDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIALALVEVYRDIILENNMDFTDIIKFFNEMAE 1123

  Fly  1168 RHNAQSILQLSRSLVLQLQTIIENK 1192
            ||||:.||||:|.||.::|.:||||
Mouse  1124 RHNAKQILQLARDLVHKVQILIENK 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049	86/197 (44%)
		PH_RUTBC	310..485	CDD:275431	105/175 (60%)
		TBC	947..1124	CDD:214540	121/176 (69%)
Sgsm1	XP_006535185.1	RUN_SGSM1	20..196	CDD:439065	94/209 (45%)
		PH_RUTBC	254..425	CDD:275431	105/175 (60%)
		TBC	<936..1105	CDD:214540	126/168 (75%)