DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1695 and sgsm3

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_998495.1	Gene:	sgsm3 / 406635	ZFINID:	ZDB-GENE-040426-2635	Length:	755	Species:	Danio rerio

Alignment Length:	260	Identity:	57/260 - (21%)
Similarity:	100/260 - (38%)	Gaps:	66/260 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   949 ALQEPKSACVS-----PASSNGGVYSVELLEQFGLNLHRIEKDVQR------CDRNYWYFANENL 1002
            |||:.:::.:|     ..|||....:.:          :||||:.|      |   :....:..:
Zfish   131 ALQKKRTSDISYREIVKNSSNDDTTAAK----------QIEKDLLRTMPTNAC---FNTLTSVGV 182

  Fly  1003 DKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHF 1067
            .|||.|:....|.:.|:||.||...:|:.||:..::|...: ..|.|:|.::.  ||      :|
Zfish   183 PKLRRVLRGLAWLYPDIGYCQGTGMVVSCLLLFLEEEDALW-MMCALIEDLLP--PS------YF 238

  Fly  1068 A--------NMRSLIQILDSEM--YDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIW 1122
            :        :.|.|.|::...:  .|.:....|.........|||..|...:....:...|::::
Zfish   239 SSTLLGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIRILLRIWDLLF 303

  Fly  1123 AAKHIASGHFVLF-LALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSILQLSRSLVLQLQ 1186
                 ..|..||| :.|.:|:...|                 |:....|:.||......|..||:
Zfish   304 -----YEGSMVLFQVTLGMLKIKED-----------------ELVSSENSASIFNTLSDLPSQLE 346

Fly 1187 1186
Zfish 347 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552
		TBC	947..1124	CDD:214540	43/195 (22%)
sgsm3	NP_998495.1	TBC	112..326	CDD:214540	51/238 (21%)
		SH3_SGSM3	488..540	CDD:212747
		RUN	567..720	CDD:280855
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900