Protein Alignment CG1695 and GAPcenA

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 1170
• Identity: 217/1170 - (18%)
• Similarity: 349/1170 - (29%)
• Gaps: 422/1170 - (36%)

  Fly   111 LELELAQESHAVSGKRSSCSSDSIIKPKLLSKGSGSSNSVTTINTVTNGAGAGPGGGGGASAPLG 175
            |..:.::.|...||:....:..::..|            :..:..|.|..|..|..||.....|.
  Fly     5 LSTKSSESSITTSGEYEIVTDSNVASP------------MEQVKQVVNQEGTQPEVGGKPPTSLS 57

  Fly   176 KYLWIRLALHEKRLAKIIEHLVSNANSYYDREALVADPDYGSILSSLLVGPCALEFTRAKTADHY 240
                 .|||             |:..:..||...: |..:...||.:               .|.
  Fly    58 -----ALAL-------------SSPEAGGDRSPTL-DMAHNRNLSDM---------------QHE 88

  Fly   241 WSDPCADELVQRHRISSGNR-------------TPPTTHR------PIINFKRSLHT-----SSE 281
            .:|...|..::|...:||.:             |.|.|..      |.:.|..:|.|     :.:
  Fly    89 MTDALKDLELERGVAASGEKSAQRLPSHQQKSLTLPLTGSGGGSVDPEMRFPCTLFTPKSEETLD 153

  Fly   282 DTSSGS------FKAC---SPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPMPG----- 332
            |.||.:      |..|   |||.|.:.......:...||           .::|||...|
  Fly   154 DASSSNRVGHSVFYDCIDASPACVEEKQDAMKPEKGDTT-----------DEEVSEIDQGCTIFS 207

  Fly   333 ---YLSLHQSIQSLTIKWTPNQLMNGYNDGDGGDKSFYWSYALNINV------DEIVYVHCHQNR 388
               ||.. .:|.:...:....::|...|.|..       |..|.|.|      :.:|.:|..::
  Fly   208 GVTYLGA-ANINAPKSETEVYRIMGELNSGSK-------SVGLKITVSIPNCSEGLVVLHDAES- 263

  Fly   389 GGDTGGTIILVGQDG----VQRPPIHFPEGG-------HLQAFLSCLETGLLPHGQLDPPLWSQR 442
                 .|||...:..    ..|.|:...|.|       |..|...|
  Fly   264 -----NTIIATYEISSIILYYRGPVDTVENGCFAFTWLHGDALFQC------------------- 304

  Fly   443 GIGKLFPWPKSVRRHILPSVMEAGGSVTDETPIDYVFRVVSKCQHEEFLASHPILELGRSSPRRK 507
               .:|      |.||..:|.:                 ||.|..:.|....|.:
  Fly   305 ---HVF------RCHIPEAVNQ-----------------VSACFQKAFQTYPPSM---------- 333

  Fly   508 HLGSCSTTGSSDCSSKSLSIDQSSCETPLIQASQSTSIELVCSTMRRQIISRAFYGWLAYCRHLS 572
               |||...:.|.:: |::.|.|.  .||    .:...|.:.|...|:.:::..|..:...|...
  Fly   334 ---SCSLNSAVDMAN-SVTSDVSG--NPL----NTAGYEFIVSLEIRERVAKNSYAAVPRDRGCF 388

  Fly   573 TVRTH----------------LSGLVNGRIMPDLAADEEGLTRGKWLAMHEDGVVTGDLELYRLV 621
            .:|.:                |..|...|....|.|.      ||.       ||..|:.|..:.
  Fly   389 KLRANTDKEVCITVKQTPSNVLQPLHIERCFGVLVAP------GKL-------VVQKDMHLIDMH 440

  Fly   622 YFGGVEP------------ELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEA 674
            ..|.::|            ..:...|||                          |..:||.|.|.
  Fly   441 SMGYIQPGGTGVATESDSNAQQSSSWPY--------------------------TIRAEWKAQEK 479

  Fly   675 IVRQ--REKEKTALAVA-----KLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGEEDQEN 732
            ...|  .|..||.|.||     :...|..|.......:      :.:.|:...::|...:.
  Fly   480 AFEQLNLESSKTNLTVAVDIVMRRIQEPVRFVIETPVT------IQSASEMRIMDHFMSKR---- 534

  Fly   733 LVLDEGENDVFDDNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREM 797
                                 |..|    ......:..|:||.:....:..|:..:|..|.|
  Fly   535 ---------------------PMTL----RFYLHLKRTEESNWKVNSIDPSEEITEQPGHQQ--- 571

  Fly   798 PRLSEKLVLEFQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGN 862
               |..|                            |.:|:::...|    ::||...|.
  Fly   572 ---SSSL----------------------------LKMGMNNLSRI----VRSSSIASI------ 595

  Fly   863 EFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQDEEESSQPATAVIITEAASLDALDD-DP-TEE 925
                       |::.|...|.  ..|:..|....|           :::..|.|.||: || ..|
  Fly   596 -----------EDDCPSDYSS--DGDEPLLSGTGE-----------VSKDCSQDTLDEWDPILRE 636

  Fly   926 FTSRKTSLMSPLNEDITVVASL------DALQE---PKSACVSPASSNGGVYSVELLEQFGLNLH 981
            :.|.|    .|.|     :|.|      :||:|   .|.|.|.........|.:.:.::.....
  Fly   637 WDSEK----RPKN-----LAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKILITKETKCET- 691

  Fly   982 RIEKDVQR---CDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSY 1043
            .|::|:.|   ..:.:........|.|..|...|.....:|||.||:..:.|.||:...:|
  Fly   692 VIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEE---- 752

  Fly  1044 SCFCKLMERMIENFPSGGAMDMHFA----------NMRSLIQILDSEMYDLMDSNGDYTHFYFCY 1098
            ..||.|:..|.:.    |..|::.|          .:..||:....::::...:.|..||.| ..
  Fly   753 DAFCVLVALMYDY----GLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIETHMY-AS 812

  Fly  1099 RWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLETYRDIILSNSMDFTDVIKFF 1162
            :|||..:........||...:|.     :..|..||| :|:.||......:  ..:||..::|:|
  Fly   813 QWFLTLYTARFPLCFVFHVLDVF-----LLDGLPVLFQVAVTLLSICESDL--RQLDFEGILKYF 870

  Fly  1163  1162
              Fly   871  870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049	21/121 (17%)
		PH_RUTBC	310..485	CDD:275431	35/199 (18%)
		TBC	947..1124	CDD:214540	43/198 (22%)
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922	31/186 (17%)
		DUF3694	377..523	CDD:463599	33/190 (17%)
		TBC	650..858	CDD:214540	49/222 (22%)
		SMC_prok_B	<876..>1087	CDD:274008
		TPH	<883..>977	CDD:464007