DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1695 and Tbc1d10a

DIOPT Version :9

Sequence 1:	NP_728346.2	Gene:	CG1695 / 33046	FlyBaseID:	FBgn0031116	Length:	1192	Species:	Drosophila melanogaster
Sequence 2:	NP_001015022.1	Gene:	Tbc1d10a / 360968	RGDID:	1311641	Length:	505	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	58/302 - (19%)
Similarity:	106/302 - (35%)	Gaps:	68/302 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   886 SADDVRLDNQDEEESSQPATAV-----IITEAASLDALDDDPTEEFTSRKTSLMSPLNEDITVVA 945
            :||::.....|.|.:......:     |:....:..||::.|.|....|::..:..||
  Rat    34 TADELSSLGSDSEANGFAERRIDKFGFIVGSQGAEGALEEVPLEVLRQRESKWLDMLN------- 91

  Fly   946 SLDALQEPKSACVS-------PASSNGGVY------SVELLEQFG----LN--------LHRIEK 985
            :.|.....|...:.       |.|..|..:      .|:|.:..|    |:        |..||:
  Rat    92 NWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIER 156

  Fly   986 DVQRCDRNYWYFAN---ENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFC 1047
            |:.|....:..|.:   .....|..|:..|.....:.||.|....:.|.||:....|. ::.|..
  Rat   157 DLHRQFPFHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQ-AFWCLV 220

  Fly  1048 KLMERMIENFPSGGAMDMHFANMRSLIQILDSE-MYDLMDSNGDYTH----------FYFCYRWF 1101
            ::.|:.:..:         ::.....|| ||.| ::.|:.......|          ..:...||
  Rat   221 QVCEKYLPGY---------YSEKLEAIQ-LDGEILFSLLQKVSPVAHKHLSRQKIDPLLYMTEWF 275

  Fly  1102 LLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLE 1142
            :..|.|.|.:..|...|::.:     ..|..::| :.|.||:
  Rat   276 MCAFARTLPWSSVLRVWDMFF-----CEGVKIIFRVGLVLLK 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552
		TBC	947..1124	CDD:214540	41/215 (19%)
Tbc1d10a	NP_001015022.1	TBC	110..313	CDD:214540	44/219 (20%)
Tbc1d10a	NP_001015022.1	VCX_VCY	404..>501	CDD:291884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900