Protein Alignment CG1695 and TBC1D16

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 678
• Identity: 147/678 - (21%)
• Similarity: 256/678 - (37%)
• Gaps: 140/678 - (20%)

  Fly   588 PDLAADEEGLTRGKWLAMHEDGVVTGDLELYRLVYFGGVEPEL------RKEVWPYL-LGHYDFG 645
            |.:|.||..:       :|..|.:|...:.:...|.....|.|      ...:..|. |...|..
  Fly    45 PTIARDESDI-------LHNPGYLTCTTKTFVDQYNSAKRPTLLLTWIPNSSLCKYTNLNADDCR 102

  Fly   646 STPEERKKQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAKLSAE-QARLAANATS----- 704
            .....|.|..::...|...|:.:.:....|   ||:::.|..:.:|..| |..|...|.|
  Fly   103 GQCNPRSKSPDSRNGYCHVTIPQTIQERDI---REEDENAADMQELKNELQPLLGGQAASIDDLT 164

  Fly   705 ---SSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGDLFDEPELGQE 766
               .:||...:.......|:|:.|..:....:.:....|:..|..:.|.:.| |...|.|:....
  Fly   165 ALLKNNPITSVNITISNPQIENSNISQSFNCITIRPDSNNCSDCTNGSGVGD-GPATDNPKWTTP 228

  Fly   767 AEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPLRL---QENC----- 823
            .....:.|||      ..|..:....|:::.........::   :..|..|||   .:||
  Fly   229 ELLAFKHNLE------FPDSGNSTPADRQKSAMKCRHFSVD---LSQMRSLRLFFNDDNCTSGQL 284

  Fly   824 -FADSETENDL-----GLGLDSSGNIL------MLSIKSSPSTSSYETVGNEFL-DMAEAKLEEE 875
             .|..|::..:     | |||....:|      :.:|.|......::.....|: ...|.|..|.
  Fly   285 VIASRESQYKILHFHYG-GLDHLAQVLHQWHCFLHNITSETGQDKFDLPYRHFMVCRPEVKKSEM 348

  Fly   876 EP-PGQLSK-----FHSA---------DDVRLDN----QDEEESSQPATAVIITEAASLDALDDD 921
            .| .|.:.|     |:..         ||:.|..    ...|:|.:......:.:..|..:..:|
  Fly   349 HPDEGDVKKITTNFFYGTLLNEKGQIEDDLLLRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFED 413

  Fly   922 PT----------EEFTSRKTSLMSPLNE-----DITVVASLDALQEPKSACVSPASSNGGVYSVE 971
            ..          ||.|.::...|||..:     .:.:|
  Fly   414 RAVLMDIKRQEYEEITRKRLYSMSPEQQIHFWKTVQIV--------------------------- 451

  Fly   972 LLEQFGLNLHRIEKDVQRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLL 1033
                       :||||.|.||...:|.   |.|.:.::|::..:...:..:.|.|||.||:||:|
  Fly   452 -----------VEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVL 505

  Fly  1034 VIFDDESLSYSCFCKLMERMIENF---PSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFY 1095
            ....:||.::.||..||:|..  |   |:...:|.:.:.:|.||:|:....|..::.:.|.....
  Fly   506 CEVQNESETFWCFVGLMQRAF--FVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQHNDSMELL 568

  Fly  1096 FCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIK 1160
            ||:||.||.||||.....|...||..|:  :..:.:|.|||.||::..|.|.:::.::...:::.
  Fly   569 FCHRWLLLCFKREFTEAVVIRMWEACWS--NYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLL 631

  Fly  1161 FFNEMAERHNAQSILQLSRSLVLQLQTI 1188
            .|:.:|...:.|.||:.:|.|:.|.:.:
  Fly   632 HFSSLAMYMDGQLILRKARGLLHQYRQL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431
		TBC	947..1124	CDD:214540	50/182 (27%)
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	68/272 (25%)