Protein Alignment CG1695 and Tbc1d15-17

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Alignment Length: 983
• Identity: 189/983 - (19%)
• Similarity: 305/983 - (31%)
• Gaps: 439/983 - (44%)

  Fly   286 GSFKACSPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPM-----PGYLSLHQSIQS--- 342
            |.|.....:||.:| |::|.|.....:|:..:.|| |.|..:|.:     .|.|||.:..:|
  Fly    16 GVFNESQLSSVEED-VQNLPQQGTGNILFTHDGVL-LKKASAEHIADLNTSGSLSLVEYSRSIAE 78

  Fly   343 -----LTIKWTPN-QLMNGYNDGDGGDKSFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILVGQ 401
                 |.::|.|| .:|...:..|.||    |:.     ||.|            :|.|......
  Fly    79 MPRRRLLLEWQPNDSIMIADDSQDQGD----WAL-----VDRI------------SGRTRTTSEC 122

  Fly   402 DGVQRPPIHFPEGGH------LQAFLSCLETGLLPH-GQ-----------LDPPLWSQRGIGKLF 448
            ......||. |.||.      ::|.|..|.:..:.| ||           :....:.|.|...||
  Fly   123 RAFNTRPIE-PSGGATTRSRVMRAQLEDLSSVEVRHRGQTIRFMRKGANGVHSEFFFQHGNADLF 186

  Fly   449 PWPKSVR-RHILPS--VMEAGGSV-----TDETPIDYVFRVV-------SKCQHEEFL------- 491
              .:|:| :|::.:  ...:||.|     |:...:...|..:       |:...|.:|
  Fly   187 --VRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGI 249

  Fly   492 ----------------ASHP-ILELG--RSSPRRKHLGSCSTTGSSDCSSKSLSIDQSSCETPLI 537
                            .|.| :|..|  ::||....:...|.:.:|.|||...|...|:.::|..
  Fly   250 LGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPAD 314

  Fly   538 QASQSTSIELVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRIMPDLAADEEG--LTRG 600
            .                               .|.|:......:||.  :||....|.|  ||..
  Fly   315 S-------------------------------ELETLNAQDEKIVNN--LPDRQRVERGHPLTET 346

  Fly   601 KWLAMH-EDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEER--KKQDETCKHYY 662
            :||... .||.::....:..|::.|||...||.|||.:||.:|.:..|..||  :::.::.::|
  Fly   347 QWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYY- 410

  Fly   663 ETTMSEWLAVEAIVRQREKEKTALAVAKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGE 727
             ...::|||:...
  Fly   411 -NMKAQWLAMTTT---------------------------------------------------- 422

  Fly   728 EDQENLVLDEGENDVFDDNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDH 792
                                                 |||
  Fly   423 -------------------------------------QEA------------------------- 425

  Fly   793 DQREMPRLSEKLVLEFQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSY 857
                                                                             
  Fly   426 ----------------------------------------------------------------- 425

  Fly   858 ETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQDEEESSQPATAVIITEAASLDALDDDP 922
                 .|....|.|.:
  Fly   426 -----NFCGYRERKCQ------------------------------------------------- 436

  Fly   923 TEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVSPASSNGGVYSVELLEQFGLNLHRIEKDV 987
                                                                        |||||
  Fly   437 ------------------------------------------------------------IEKDV 441

  Fly   988 QRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKL 1049
            :|.||:..:||   |.||..|:.::.|||..:.|:||:|||.||:||:|.|..:|..::.||...
  Fly   442 KRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGF 506

  Fly  1050 MERMIENFPSGGA-MDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDD 1113
            ||.:..||....| |...||.:|.||:..::.:::.|.|: |..:.|||:||.|:.:||||..:|
  Fly   507 MELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSH-DSDNMYFCFRWLLVWYKRELNSED 570

  Fly  1114 VFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSILQLS 1178
            |...||.:|.  .:...:|.|..::|:|:....:|:.:..:||:::|..||::...:.|..||::
  Fly   571 VLKLWECLWT--RLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVA 633

  Fly  1179 RSLVLQLQ 1186
            ..:.|||:
  Fly   634 EGIYLQLK 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431	49/221 (22%)
		TBC	947..1124	CDD:214540	61/180 (34%)
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	89/526 (17%)