Protein Alignment CG1695 and tbc

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_608395.6
• Gene: tbc / 318059
• FlyBaseID: FBgn0052506
• Length: 1155
• Species: Drosophila melanogaster
• Alignment Length: 1255
• Identity: 816/1255 - (65%)
• Similarity: 931/1255 - (74%)
• Gaps: 183/1255 - (14%)

  Fly    17 NASGDVSNAETELKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSHGLRRRAL 81
            ||.|      ::.||||||||||||||||||||||||||||||||||||||||||||.|||||||
  Fly     5 NADG------SDYKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSQGLRRRAL 63

  Fly    82 GLFKTSSTTALIQKIAKICPEADYVSRRLLELELAQESHAVSGKRSSCSSDSIIKPKLLSKGSGS 146
            |||||||||||:.||||.||||:::|:.:.|:|.:..|     ||||.||||..:|.:|.|.|.:
  Fly    64 GLFKTSSTTALLHKIAKSCPEAEHISKLVQEIEASDPS-----KRSSSSSDSFQRPPMLKKSSSN 123

  Fly   147 SNSVTTINTVTNGAGAGPGGGGGASAPLG---------KYLWIRLALHEKRLAKIIEHLVSNANS 202
            |     ::|.||.|.:........|....         |||||||||:||||.||||:|||||:|
  Fly   124 S-----MSTGTNAAASTSSASASISVSASTSSMSLASMKYLWIRLALYEKRLTKIIEYLVSNASS 183

  Fly   203 YYDREALVADPDYGSILSSLLVGPCALEFTRAKTADHYWSDPCADELVQRHRISSGNRTPPTTHR 267
            :|||::||||.||||||||||||||||||||||||||||:||.||||||||||||..|:..|..|
  Fly   184 FYDRDSLVADSDYGSILSSLLVGPCALEFTRAKTADHYWTDPHADELVQRHRISSCRRSSSTCSR 248

  Fly   268 P-IINFKRSLHTSSEDTSSGSFKACSPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPMP 331
            | ||||||||:|||::..:||||:.:.||||||||||||||::.|||||||||.||||||:||||
  Fly   249 PAIINFKRSLNTSSDEAGTGSFKSIASASVAKDYVESLHQNAKATLLYGKNNVQVLPKDVAEPMP 313

  Fly   332 GYLSLHQSIQSLTIKWTPNQLMNGYNDGDGG---DKSFYWSYALNINVDEIVYVHCHQNRGGDTG 393
            |||||||.||:||||||||||||||.:.:..   ||..:|:|||||||||||||||||:||.|:|
  Fly   314 GYLSLHQHIQTLTIKWTPNQLMNGYTEAEEAEDIDKDAFWAYALNINVDEIVYVHCHQSRGEDSG 378

  Fly   394 GTIILVGQDGVQRPPIHFPEGGHLQAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHI 458
            ||:||||||||||||||||||||:|.|||||||||||||||||||||||||||:|.||:|:||.|
  Fly   379 GTVILVGQDGVQRPPIHFPEGGHMQQFLSCLETGLLPHGQLDPPLWSQRGIGKMFLWPRSMRRRI 443

  Fly   459 LPSVMEAGGSVTDETPIDYVFRVVSKCQHEEFLASHPILELGRSSPRRKHLGSCSTTGSSDCSSK 523
            ||||||:    .||||||||||:|||.:||||.|:|.||:..||:|||..|.|||||||||||:|
  Fly   444 LPSVMES----VDETPIDYVFRIVSKSRHEEFAATHSILDFVRSTPRRAQLSSCSTTGSSDCSNK 504

  Fly   524 SLSIDQSSCETPLI------------QASQSTSIELVCSTMRRQIISRAFYGWLAYCRHLSTVRT 576
            ||||||...|:|||            || ||||||:|||||||||||||||||||||||||||||
  Fly   505 SLSIDQFPMESPLILQQQQQQQQQLLQA-QSTSIEMVCSTMRRQIISRAFYGWLAYCRHLSTVRT 568

  Fly   577 HLSGLVNGRIMPDLAADEEGLTRGKWLAMHEDGVVTGDLELYRLVYFGGVEPELRKEVWPYLLGH 641
            ||||||:|||.|::.|||||||:.:|..::.:||:....|.|||||||||:||||:|||||||||
  Fly   569 HLSGLVHGRITPEMKADEEGLTKERWQLLNVNGVLENATEFYRLVYFGGVQPELRQEVWPYLLGH 633

  Fly   642 YDFGSTPEERKKQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAKLSAEQARLAANATSSS 706
            |.||||.|:||||||||||||||||||||||:|||:||||||||.||||||        :.::|.
  Fly   634 YAFGSTTEDRKKQDETCKHYYETTMSEWLAVDAIVQQREKEKTARAVAKLS--------SGSNSG 690

  Fly   707 NPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDVFDDNDFSDISDPGDL-FDEPELGQEAEEQ 770
            |.....|     ..||.|.           :.||:||:  |.||||||||| |||    |:.::|
  Fly   691 NDRTVRA-----ADLEAGG-----------DLENEVFE--DISDISDPGDLEFDE----QQQQQQ 733

  Fly   771 EQ------------------------SNLEEEVFEKQEDEEDQEDHDQR----EMPRLSEKLVLE 807
            :|                        |...:|.| .:.||.|:||:.|:    |....||..:.:
  Fly   734 QQAECAVSGNHLTVKPIPRAMKTSTDSGHVDESF-NELDEPDEEDNKQKQQQDEKISESESKLPD 797

  Fly   808 FQNID---NMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAE 869
            ::.::   |.||     :|                          |:.:.|||||||
  Fly   798 YRKLEEQINQEP-----SC--------------------------SASTASSYETVG-------- 823

  Fly   870 AKLEEEEPPGQL-------------SKFHSADDVRLDNQDEEESSQP-----ATAVIITEAASLD 916
                    ||::             .::.||||::|  .|:|::.:|     |.|||||: ||:|
  Fly   824 --------PGEVHQRPNSDTRSVLSPEYLSADDLQL--PDDEDAVRPPPPPAAAAVIITK-ASVD 877

  Fly   917 ALDDDPTEEFTSRKTSLMSPLNEDI----TVVASLDALQEPKSACVSPASSNGGVYSVELLEQFG 977
            ..:.:.:.:  :.:...||||.|..    ....::||||:|||||.|||||||||||.|||||||
  Fly   878 ITNWERSPK--AAEGDQMSPLEEQAGESGGAGVNMDALQQPKSACASPASSNGGVYSSELLEQFG 940

  Fly   978 LNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLS 1042
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   941 LNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLS 1005

  Fly  1043 YSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKR 1107
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly  1006 YSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYRWFLLDFKR 1070

  Fly  1108 ELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQ 1172
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly  1071 ELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQ 1135

  Fly  1173 SILQLSRSLVLQLQTIIENK 1192
            |:|||:||||||||.|||||
  Fly  1136 SVLQLARSLVLQLQMIIENK 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049	131/202 (65%)
		PH_RUTBC	310..485	CDD:275431	141/177 (80%)
		TBC	947..1124	CDD:214540	172/176 (98%)
tbc	NP_608395.6	RUN_SGSM1_like	21..214	CDD:439049	131/202 (65%)
		PH_RUTBC	292..466	CDD:275431	141/177 (80%)
		TBC	923..1087	CDD:214540	162/163 (99%)