Protein Alignment CG1695 and Tbc1d2

DIOPT Version :9

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_006238118.1
• Gene: Tbc1d2 / 313234
• RGDID: 1306860
• Length: 924
• Species: Rattus norvegicus
• Alignment Length: 607
• Identity: 116/607 - (19%)
• Similarity: 224/607 - (36%)
• Gaps: 131/607 - (21%)

  Fly   649 EERKKQDETCKHYYE------TTMSEWLAVE----AIVRQREKEKTALAVAKLSAEQARLAANAT 703
            ::.|:|..|...:.:      |...:.:|:|    .:.::.:.:|..:.:...:.|.|:....|:
  Rat   284 QKPKRQSNTFPFFSDGLARSRTAQEKVVALEQQVLMLTKELKSQKELVIILHKALEAAQQEKRAS 348

  Fly   704 SS--------------SNPHQKLANGSQQLQLEHGNGEEDQENLVLDEG--ENDVFDDNDFSDIS 752
            |:              .:..:::|..:|:::..    |:|:|.||.:.|  |..|........:
  Rat   349 SAYLAATEDRDRLELVRHKVRQIAELNQRVEAL----EQDRERLVHEAGLREQQVQALQQHVQL- 408

  Fly   753 DPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPL 817
                |.|:.:..|:...:....|.|::.:.|..:....|.       ||::..||... |:||..
  Rat   409 ----LMDKNQAKQQVICKLSQKLTEDLAQPQPADATNGDF-------LSQQERLEHLK-DDMEAY 461

  Fly   818 RLQENCFADSE-----------TENDLGLGLDSSGNILMLSIKSSPSTSSY--------ETVGNE 863
            |.| |.|.:||           .|.:..|    ......|..::....|.|        |..|.|
  Rat   462 RTQ-NRFLNSEIHQVTKIWRKVAEKEKAL----LTKCAYLQARNCQVESKYLAGLRRLQEAAGAE 521

  Fly   864 FLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQDEEES----SQPATAV----IITEAASLD---- 916
            ..|..|...:..:...|.....::|.|.|....|.:.    :.|...|    ::.:..:|:
  Rat   522 PGDFPELLQQLVQEALQWEAGEASDSVGLSPVSEYDDYGFLTVPDYEVEDLKLLAKIQALEVRSH 586

  Fly   917 ---ALD--DDPTEEFTSRKTSLMSPLNEDITVVASLDALQEPK---------------SACVSPA 961
               ||:  :.|..:..:..|.||........:.|.:.....|:               |.|....
  Rat   587 HLLALEAVERPLRDRWATLTELMPSAELKQLLRAGVPREHRPRVWRWLVHRRVQHLHSSGCYQEL 651

  Fly   962 SSNGGVYSVELLEQFGLNLHRIEKDVQRCDRNYWYFANENL--------DKLRNVISTYVWEHLD 1018
            .:.|.........|..|:|:|.            :..|::.        ||||.|:..:.|::..
  Rat   652 LARGRACEHPAARQIELDLNRT------------FPTNKHFTCPTSSFPDKLRRVLLAFSWQNPT 704

  Fly  1019 VGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYD 1083
            :||.||:..|.|..|::.:||..::.|...::|.::........:.....:.| ::|.|.||...
  Rat   705 IGYCQGLNRLAAIALLVLEDEESAFWCLVAIVETILPAEYYSKTLTASQVDQR-VLQDLLSEKLP 768

  Fly  1084 LMDSNGDYTHF---YFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLF-LALALLETY 1144
            .:.::....|.   ...:.|||:.|...|:.|.:...|:..     :..|..|:| .|||:.:..
  Rat   769 RLTAHLGQRHVDLSLITFNWFLVIFADSLISDILLRVWDAF-----LYEGTKVVFRYALAIFKYN 828

  Fly  1145 RDII--LSNSMDFTDVIKFFNE 1164
            .:.|  |.:|::....::||.:
  Rat   829 EEAILRLQDSLEIYQYLRFFTK 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	11/87 (13%)
		TBC	947..1124	CDD:214540	39/202 (19%)
Tbc1d2	XP_006238118.1	PH_TBC1D2A	44..145	CDD:269966
		PH	44..137	CDD:278594
		TBC	621..833	CDD:214540	45/229 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900