Protein Alignment CG1695 and Tbc1d16

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_006532756.1
• Gene: Tbc1d16 / 207592
• MGIID: 2652878
• Length: 782
• Species: Mus musculus
• Alignment Length: 661
• Identity: 162/661 - (24%)
• Similarity: 255/661 - (38%)
• Gaps: 151/661 - (22%)

  Fly   648 PEER-KKQDETCKHYYETTMSEWLAVEAIVRQREKEKTAL-AVAKLSAEQARL------------ 698
            |..| ::|||....|.....|   .|....|.|.:..|:| |:.:.|..:.|.
Mouse    82 PNSRIQRQDEEALRYITPESS---PVRKAPRPRRRRTTSLGALYQPSPTEPRPPLIPKDEDILVV 143

  Fly   699 ------AANATSSSNPHQKLANG---------SQQLQLEHG------------NGEEDQENLVLD 736
                  .|:.:.:....:|||.|         ||.:..:.|            :|.|.:...|.:
Mouse   144 VQNTQDTAHISPTDEDGEKLAQGPEVDGALSTSQPVHSDSGILSTVSSQDGTEDGREPRPEAVEE 208

  Fly   737 EGENDVFDD---NDFSDISDPGDLFDEPEL-----GQEAEEQEQSNLEEE---------VFEKQE 784
            ||..::..|   .|.|..|| .|.|..|..     ...||....:.||.|         |...:|
Mouse   209 EGSLELSADGVSRDSSFDSD-SDAFSSPFCLSPISAALAEGNSSAFLESEGSRQAINCWVGTPKE 272

  Fly   785 DEEDQEDHDQR----------EMPRLSEK---LVLE-----FQ-NIDNMEPLRLQENCFADSETE 830
            ........|..          :.||..|.   ..||     |: ::.:|..|||   .|:|...
Mouse   273 GISSPSSSDANLRFPDSNGLLQTPRWDEPQRGCALEQICGVFRVDLGHMRSLRL---FFSDEAC- 333

  Fly   831 NDLGLGLDSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAKLEEEEPPGQLSKFHSADDVRLDNQ 895
                    :||.:::.|.:|......:...|   ||    ||.|   ..|..||.:...:| |.|
Mouse   334 --------TSGQLVVASRESQYKIFHFHHGG---LD----KLSE---VFQQWKFCTETHLR-DQQ 379

  Fly   896 --DEEESSQ--------PATAVIITE--------AASLDALDD--DPTEEFTSRKTSLMSPLNED 940
              ||....|        |::.:...|        :|.|:.|:|  ...||:..|:......:  |
Mouse   380 VTDERTCMQFSIRRPKLPSSEIHPEESLYRRLDVSAWLNHLNDLGQVEEEYKLRQAIFFGGI--D 442

  Fly   941 ITV----------VASLDALQEPKSACVSPASSNGGVYSVELL-----EQ--FGLNLH-RIEKDV 987
            :::          ..|.::..|.:.|..|...........:.|     ||  |..|:. .::|||
Mouse   443 VSIRGEVWPFLLHYYSHESTSEEREALRSQKRKEYAAIQQKRLSMTPEEQRAFWRNVQFTVDKDV 507

  Fly   988 QRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKL 1049
            .|.|||..:|.   |.|::.:|.::..|...:..:||.|||.|||||:|....|||.::.||..|
Mouse   508 VRTDRNNQFFRGEDNPNVESMRRILLNYAVYNPAIGYSQGMSDLVAPILAEVLDESDTFWCFVGL 572

  Fly  1050 MERMI-ENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNG-DYTHFYFCYRWFLLDFKRELVYD 1112
            |:..| .:.|....|:.....:|.|:::.....|..:.|.| |.....||:||.||.||||....
Mouse   573 MQNTIFVSSPRDEDMERQLLYLRELLRLTHQRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEA 637

  Fly  1113 DVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNEMAERHNAQSILQL 1177
            :....||..||  |..:.:|.||:.:|::..|.|.::...:....::..|..:|...|.:.:|:.
Mouse   638 EALRIWEACWA--HYQTDYFHLFICVAIVAIYGDDVIEQQLATDQMLLHFGNLAMHMNGELVLRK 700

  Fly  1178 SRSLVLQLQTI 1188
            :|||:.|.:.:
Mouse   701 ARSLLYQFRLL 711

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431
		TBC	947..1124	CDD:214540	60/189 (32%)
Tbc1d16	XP_006532756.1	TBC	439..667	CDD:214540	68/231 (29%)