Protein Alignment CG1695 and tbc-12

DIOPT Version :9

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_508458.1
• Gene: tbc-12 / 180556
• WormBaseID: WBGene00044061
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 624
• Identity: 127/624 - (20%)
• Similarity: 213/624 - (34%)
• Gaps: 173/624 - (27%)

  Fly   646 STPEERK-KQDETCKHYYETTMSEWLAVEAIVRQREKEKTALAVAK-----LSAEQARLAANATS 704
            ||.:|.| ::....:..||:...:......|.........|.:.||     |.:......|:.:|
 Worm    63 STAQETKFRRGHIRRSSYESAQIQLNFARRITTANGTPALAPSAAKCLDEPLCSLSLNTRADCSS 127

  Fly   705 SSNPHQKLANGSQQLQLEHGNG--EEDQENLVLDEGENDVFDDNDFSDISDPGDLFDEPELGQEA 767
            ||         |:|.|.:.|.|  |.|.:...||..          |::||    ||||....|.
 Worm   128 SS---------SEQDQYDSGIGCTESDSKRSSLDRR----------SELSD----FDEPPSKPET 169

  Fly   768 EEQEQ-SNLEEEVFEKQEDEEDQEDHDQREMPRLSEKLVLEFQNIDNMEPLRLQENCFADSETEN 831
            ..:.: .|..:..|.:.::|:    |..:                           .|.....::
 Worm   170 LSKSRFFNFPKNFFSRNKEEK----HGWK---------------------------MFGSRNKQS 203

  Fly   832 DLGLGLDSSGNILMLSIKSSPSTSSYETVGNE--FLDMAE-AKLEEEEPPGQLSKFHSADDVRLD 893
            .:   :.::|.||.......||.|:.|...::  :||:.| ||.:|:.          |:..||.
 Worm   204 GV---MATTGLILEERPSGLPSKSADEAAHHKQMYLDILEQAKKKEQR----------AEKERLQ 255

  Fly   894 NQDEEESSQPATAV--------IITEAASLDALDDDPTEEF-------TSRKTSLMSPLNEDITV 943
            .:.|::..:..||.        |:.:...:.  |.....|.       ..|.......:...|.:
 Worm   256 AKAEQKRLEEQTAAHCRVWVEQILPKWEEMK--DSKRCRELWWQGVPAKVRGELWFLTIGNQIEI 318

  Fly   944 VASL-DALQEPKSACVSPASSNGGVYSVELLEQFGLNLHRIEKDVQRCDRNYWYFANEN--LDKL 1005
            ...| |.|.:.....::...:.....|.|..|   .::.:|..|..|...:...|..:.  .|.|
 Worm   319 TKELYDGLMDQAEEKIAKQLAEQNKNSAERKE---TSVTQIHLDATRTFTSLGMFQKDGPYYDHL 380

  Fly  1006 RNVISTYVWEHLDVGYMQGMCDLVAPLLVIFDDESLSYSCFCKLMERMIENFPSG---GAMDMHF 1067
            ..::|.|.....|:||:|.|..:.|.||:..|... ::..|..|::|.:::...|   ..|..:|
 Worm   381 LKLLSAYAILRPDIGYVQSMTFIAAVLLIQMDPYP-AFISFANLLDRSLQSAFFGLKQPQMTEYF 444

  Fly  1068 -ANMRSLIQILDS--EMYDLMDSNGDYTHFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIAS 1129
             |..|.|.|.|.:  :..|.:|...|    .:...|....:.:.|..|.....|:|     :...
 Worm   445 IAYDRYLEQELPALHQHLDKLDVRPD----LYLIEWTFAMYAKSLPLDVTCRIWDV-----YFRD 500

  Fly  1130 GHFVLF-LALALLETYRDIILSNSMDFTDVIKF-------------------------------- 1161
            |...|| .||.:|..|...:|  :|||.|.::|
 Worm   501 GEEFLFKAALGILRMYEPKLL--TMDFDDCVEFLTKLPNTLTGAELFRNIEPFMRPYNGESSRSK 563

  Fly  1162 ------FNEMAER-------------HNAQSILQLSRSL 1181
                  |.|:.||             ||.|. |::|:||
 Worm   564 KRFSQIFQEIDERVNPGGTTARTQITHNVQE-LKMSKSL 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	13/70 (19%)
		TBC	947..1124	CDD:214540	42/185 (23%)
tbc-12	NP_508458.1	TBC	295..521	CDD:214540	51/238 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810