Protein Alignment CG1695 and tbc-14

DIOPT Version :9

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001317776.1
• Gene: tbc-14 / 174986
• WormBaseID: WBGene00008444
• Length: 630
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 140/621 - (22%)
• Similarity: 237/621 - (38%)
• Gaps: 141/621 - (22%)

  Fly   648 PEERKKQDETCKHYYETTMS----------EWLAVE----AIVRQREKEKTALAVAKLSAEQARL 698
            |....|..|..|.|...|:|          ||...|    :.|...:...|.:..|:...|:.:.
 Worm    42 PNVAAKLGEDSKEYIPGTLSIVEKSSGVFIEWKPSEDAETSWVMTSDDGNTEMVHARSPEEKQKC 106

  Fly   699 AANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGENDV---FDDNDFSDISD------- 753
            .|....|.:.:...:..:.:.:.:.|:|......|:..:|.:.|   |.:...::..|
 Worm   107 GARVAFSMDVNDLSSFRNDEPKRDSGSGGFPSIRLICRDGSSQVPLFFKNTTTAEFLDRLQGYIT 171

  Fly   754 ------PGDLFDEPELGQEAEEQEQSNLEE---------------------EVFEKQEDE----- 786
                  ...|....:...||..:..|.|:|                     ::....:|:
 Worm   172 LRRSHRDSHLVIVVDQKSEALAKSVSMLDENGDILSRFMQNPYMTAMTGFSKITSFVQDQVIPSV 236

  Fly   787 -EDQEDHDQREMPRLSEKLVL-------------EFQNIDNMEPLRLQENCFADSETENDLGLGL 837
             .|.:...|.|..||..:|.|             ||:.:..:| |..:...:.:.....||
 Worm   237 LNDTDAVTQEEKIRLMRELRLAEEQMRVHSDAAGEFEVVTQLE-LPPRPEIYRELPVSKDL---- 296

  Fly   838 DSSGNILMLSIKSSPSTSSYETVGNEFLDMAEAKLEEEEPPGQLS--KFHSADDVRLDNQDEEES 900
               .|...||..|......:....|.|.....|:|.:|.....|.  ::|.:|   .|.|
 Worm   297 ---WNSFKLSNGSYDPMKLHHLKMNVFRGGLNAELRKEAWKCLLGYRQWHESD---TDFQ----- 350

  Fly   901 SQPATAVIITEAASLDALDDDPTEEFTSRKTSLMSPLNEDITVVASLDALQEPKSACVSPASSNG 965
                     |..|.|       .:::.:.|...|| :.||          ||.:
 Worm   351 ---------TRRAEL-------AKQYENMKKQWMS-VTED----------QEKR----------- 377

  Fly   966 GVYSVELLEQFGLNLHRIEKDVQRCDRNYWYFA---NENLDKLRNVISTYVWEHLDVGYMQGMCD 1027
                   ..:|......:||||.|.||...:|.   |.||..|.||:.|||..:.|:||:|||.|
 Worm   378 -------FTKFVKRKSLVEKDVARTDRTVPFFQGDDNVNLVHLHNVLMTYVMYNFDLGYVQGMSD 435

  Fly  1028 LVAPLLVIFDDESLSYSCFCKLMERMIENFPSGGA-MDMHFANMRSLIQILDSEMYDLMDSNGDY 1091
            ..:|||.:..||..::.||..|||...:||.:..| :.:....:|.|:.|::.::.:.::|...
 Worm   436 FASPLLFVMKDEVDTFWCFVGLMELTQKNFETDQAFIKLQMNQLRDLVMIINPKLANYLESEKS- 499

  Fly  1092 THFYFCYRWFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFT 1156
            ...|||:||.|:.||||..:.|....|||:|:.:  ....|:|.:.:|:|::..:||:.|....|
 Worm   500 DDMYFCFRWVLVWFKREFSFLDTCKLWEVLWSGQ--PCPRFLLLICVAILDSQTNIIIDNQFGLT 562

  Fly  1157 DVIKFFNEMAERHNAQSILQLSRSLVLQLQTIIENK 1192
            :::|..|:::.......||..:.::..|| :..:||
 Worm   563 EILKHINDLSMHLKVDEILTAAEAIFHQL-SASQNK 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN	63..237	CDD:280855
		PH_RUTBC	310..485	CDD:275431
		SRP68-RBD	<648..>713	CDD:304552	16/78 (21%)
		TBC	947..1124	CDD:214540	59/180 (33%)
tbc-14	NP_001317776.1	DUF3548	51..197	CDD:371881	23/145 (16%)
		TBC	320..555	CDD:214540	81/290 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810