Protein Alignment CG1695 and LOC1273870

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_061519597.1
• Gene: LOC1273870 / 1273870
• VectorBaseID: AGAMI1_012278
• Length: 1131
• Species: Anopheles gambiae
• Alignment Length: 1198
• Identity: 777/1198 - (64%)
• Similarity: 904/1198 - (75%)
• Gaps: 118/1198 - (9%)

  Fly    28 ELKERLIASVKKEVKQLMEEAVTKKYVHEESSSVTSLCGAVEACLSHGLRRRALGLFKTSSTTAL 92
            :.||:|||:|||||||:|||||||||:||||.|||:||.|||||||.||||||||||||||||||
Mosquito    19 DFKEKLIAAVKKEVKQVMEEAVTKKYIHEESCSVTALCAAVEACLSQGLRRRALGLFKTSSTTAL 83

  Fly    93 IQKIAKICPEADYVSRRLLELELAQESHAVSGKRSSCSSDSIIKPKLLSKGSGSSNSVTTINTVT 157
            :.|:||.||||..:||::.::|     ::...||||.||||..||.:|.|||.:|.|.||
Mosquito    84 LHKVAKHCPEAACISRKVQDIE-----NSDPNKRSSSSSDSTNKPPILKKGSSNSVSTTT----- 138

  Fly   158 NGAGAGPGGGGGASAPLGKYLWIRLALHEKRLAKIIEHLVSNANSYYDREALVADPDYGSILSSL 222
                      ...:.|:.|||||||||:||:|::||:||||||..||:|::||||||||||||||
Mosquito   139 ----------PPQTPPVVKYLWIRLALYEKKLSRIIDHLVSNATRYYERDSLVADPDYGSILSSL 193

  Fly   223 LVGPCALEFTRAKTADHYWSDPCADELVQRHRISSGNRTPPTTHRPIINFKRSLHTSSEDTSSGS 287
            |||||||:::|||||||:|:||.||||||||||||.|.|||...||::|||||||||||:.|..|
Mosquito   194 LVGPCALDYSRAKTADHFWTDPPADELVQRHRISSSNPTPPAYRRPMLNFKRSLHTSSEEGSMAS 258

  Fly   288 FKACSPASVAKDYVESLHQNSRTTLLYGKNNVLVLPKDVSEPMPGYLSLHQSIQSLTIKWTPNQL 352
            ||:.|.||.:||||||||||||.||||||||||||||||||||||||||||::||||||||||||
Mosquito   259 FKSNSLASASKDYVESLHQNSRATLLYGKNNVLVLPKDVSEPMPGYLSLHQTVQSLTIKWTPNQL 323

  Fly   353 MNGYNDGDGGDKSFYWSYALNINVDEIVYVHCHQNRGGDTGGTIILVGQDGVQRPPIHFPEGGHL 417
            ||||.:.:..|||.||:||||:||||||||||||.|||||||||||||||||||||||||||||:
Mosquito   324 MNGYTESENIDKSSYWAYALNVNVDEIVYVHCHQARGGDTGGTIILVGQDGVQRPPIHFPEGGHM 388

  Fly   418 QAFLSCLETGLLPHGQLDPPLWSQRGIGKLFPWPKSVRRHILPSVMEAGGSVTDETPIDYVFRVV 482
            .|||||||||||||||||||||||||||::||||:..||..|||::|    ..||.|||||||||
Mosquito   389 AAFLSCLETGLLPHGQLDPPLWSQRGIGRIFPWPQKSRRRPLPSLLE----TNDEMPIDYVFRVV 449

  Fly   483 SKCQHEEFLASHPILELGRSSPR-RKHLGSCSTTGSSDCSSKSLSIDQSSCETPLIQASQSTSIE 546
            :|...:||||:|.||||||:||| |..|.||||..||||||||||||..|.::|..|.:|||||.
Mosquito   450 NKGNTDEFLATHSILELGRTSPRYRAQLSSCSTNESSDCSSKSLSIDAMSIDSPNPQTTQSTSIA 514

  Fly   547 LVCSTMRRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRIMPDLAADEEGLTRGKWLAMHE-DGV 610
            ||||||:|||||||||||||||||||||||||||||||||.|:..| |:||||.:|.::|: :||
Mosquito   515 LVCSTMKRQIISRAFYGWLAYCRHLSTVRTHLSGLVNGRITPETGA-EQGLTRSRWESLHDGNGV 578

  Fly   611 VTGDLELYRLVYFGGVEPELRKEVWPYLLGHYDFGSTPEERKKQDETCKHYYETTMSEWLAVEAI 675
            |..|.|:|||||:||||.::||||||||||||.|||||:||.:.|||.|||||||||||||||||
Mosquito   579 VADDQEVYRLVYYGGVEHDIRKEVWPYLLGHYSFGSTPDERAELDETAKHYYETTMSEWLAVEAI 643

  Fly   676 VRQREKEKTALAVAKLSAEQARLAANATSSSNPHQKLANGSQQLQLEHGNGEEDQENLVLDEGEN 740
            ||||:|||||:||||||       :.:.|..|..:.|   .|....|.|.||:::|     |.||
Mosquito   644 VRQRDKEKTAVAVAKLS-------SGSGSMENRSKTL---DQDADGEQGEGEDEEE-----EMEN 693

  Fly   741 DVFDDNDFSDISDPGDLFDEPELGQEAEEQEQSNLEEEVFEKQEDEEDQEDHDQREMPRLS-EKL 804
            :||::|.|||:|:|           |.|.:|:|           |.:.|...:...:|.:: :.|
Mosquito   694 EVFEENGFSDMSEP-----------EVEGEERS-----------DAKVQLTKETITLPVVAQDAL 736

  Fly   805 VLE-------FQNIDNMEPLRLQENCFADSETENDLGLGLDSSGNILMLSIKSSPSTSSYETVGN 862
            .:|       .::.|..|          :.|.|.|    .||:        |||||.|||.||||
Mosquito   737 TVETAGGAGAAESADRGE----------EQEQEQD----FDSN--------KSSPSDSSYATVGN 779

  Fly   863 EFLDMAE--AKLEEEEPPGQLS-------------------KFHSADDVRLDNQDEEESSQPATA 906
            :|:|:|:  :.:.||:..|..|                   :..:..|...|..|..:|.:...|
Mosquito   780 DFIDVADIISPMGEEDSGGARSLGAVERMQEGEDEDGVTSGEGGAGPDEEEDEPDSPKSLEQPRA 844

  Fly   907 VIITEAASLDALDDDPTEEFTSRKTSLMSPLNED--ITVVASLDALQEPKSACVSPASSNGGVYS 969
            ||:|: ||:|.....|.|.........:|.|.|:  .....:||:|||||||||||||||||:||
Mosquito   845 VIVTD-ASIDVTMLLPGEVRELNNNHTLSTLAEEGGNQQQPALDSLQEPKSACVSPASSNGGIYS 908

  Fly   970 VELLEQFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVISTYVWEHLDVGYMQGMCDLVAPLLV 1034
            .||||.||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||
Mosquito   909 SELLESFGLNLHRIEKDVQRCDRNYWYFANENLDKLRNVICTYVWEHLDVGYMQGMCDLVAPLLV 973

  Fly  1035 IFDDESLSYSCFCKLMERMIENFPSGGAMDMHFANMRSLIQILDSEMYDLMDSNGDYTHFYFCYR 1099
            |||||||||.|||:.|||||||||:||||||||||||||||||||||||||.::|||||||||||
Mosquito   974 IFDDESLSYGCFCRFMERMIENFPNGGAMDMHFANMRSLIQILDSEMYDLMHAHGDYTHFYFCYR 1038

  Fly  1100 WFLLDFKRELVYDDVFATWEVIWAAKHIASGHFVLFLALALLETYRDIILSNSMDFTDVIKFFNE 1164
            ||||||||||:|.|:|:.|||||||||:||.|||||||||||||||||||||||||||:||||||
Mosquito  1039 WFLLDFKRELIYADIFSVWEVIWAAKHVASAHFVLFLALALLETYRDIILSNSMDFTDIIKFFNE 1103

  Fly  1165 MAERHNAQSILQLSRSLVLQLQTIIENK 1192
            ||||||..|:|:|:||||||||||||||
Mosquito  1104 MAERHNTPSVLKLARSLVLQLQTIIENK 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049	121/193 (63%)
		PH_RUTBC	310..485	CDD:275431	142/174 (82%)
		TBC	947..1124	CDD:214540	159/176 (90%)
LOC1273870	XP_061519597.1	None