Protein Alignment CG1695 and TBC1D3E

DIOPT Version :10

• Sequence 1: NP_728346.2
• Gene: CG1695 / 33046
• FlyBaseID: FBgn0031116
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: XP_054170649.1
• Gene: TBC1D3E / 102723859
• HGNCID: 27071
• Length: 610
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 65/308 - (21%)
• Similarity: 92/308 - (29%)
• Gaps: 117/308 - (37%)

  Fly   495 PILELGRSSPRRKHLGSCSTTG--SSDCSSKSL-SIDQSSCETPLIQASQSTSIELVCSTMRRQI 556
            |.||..|:||   ..||....|  .:.|||.:| .:..|..|.|.:.|.::..|        |:.
Human    79 PELERDRASP---FWGSAPRLGPLQAPCSSSALPGLPYSETELPPLTAREAKQI--------RRE 132

  Fly   557 ISRAFYGWLAYCRHLSTVRTHLSGLVNGRIMPDLAADEEGLTRGKWLAMHEDGVVTGDLELY--- 618
            |||                                       :.||:.|      .||.|.|
Human   133 ISR---------------------------------------KSKWVDM------LGDWEKYKSS 152

  Fly   619 -RLV--YFGGVEPELRKEVWPYLL----------GHYDFGSTPEERKKQDETC------------ 658
             :|:  .:.|:...:|..:|..||          |.|..  ..|:.|:..|..
Human   153 RKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQI--MKEKGKRSSEHIQRIDRDVSGTLR 215

  Fly   659 KHY-----YETTMSEWLAVEAIVRQREKEK---------TALAVAKLSAEQARLAANATSSSNPH 709
            ||.     |.|...|.|.:.....:...|.         .||.:..|..|.|..|.        .
Human   216 KHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWAL--------V 272

  Fly   710 QKLANGSQQLQLEHG------NGEEDQENLVLDEGENDVFDDNDFSDI 751
            |.||:....||..|.      .|.:||:..|:...:.......|..|:
Human   273 QLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDL 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1695	NP_728346.2	RUN_SGSM1_like	39..233	CDD:439049
		PH_RUTBC	310..485	CDD:275431
		TBC	947..1124	CDD:214540
TBC1D3E	XP_054170649.1	TBC	160..373	CDD:214540	35/171 (20%)
		PHA03381	<417..>529	CDD:177618