DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mal and ABA3

DIOPT Version :9

Sequence 1:	NP_001285493.1	Gene:	mal / 33045	FlyBaseID:	FBgn0002641	Length:	781	Species:	Drosophila melanogaster
Sequence 2:	NP_001322902.1	Gene:	ABA3 / 838224	AraportID:	AT1G16540	Length:	842	Species:	Arabidopsis thaliana

Alignment Length:	859	Identity:	282/859 - (32%)
Similarity:	413/859 - (48%)	Gaps:	139/859 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PEFSASEQSQIDAEFSRLASNKSVYLDHAGTTLYAESQVTAAAEQLQRNVICNPHT----CRLTG 66
            |:...:.|...|.||.|| ....|||||||:|||:|.|:....:....||..|||:    ...|.
plant    15 PDGPKNIQEIRDTEFKRL-DKGVVYLDHAGSTLYSELQMEYIFKDFTSNVFGNPHSQSDISSATS 78

  Fly    67 DFVDQVRFKILEFFNTTAEDYHVIFTANATAALSLVAENFDFGSSGEFHFCQENHTSVLGMRE-- 129
            |.:...|.::||:||.:.|||..:||:.|||||.||.|.|.:.....|.:..|||.||||:||
plant    79 DLIADARHQVLEYFNASPEDYSCLFTSGATAALKLVGETFPWTQDSNFLYTMENHNSVLGIREYA 143

  Fly   130 -----------------------------RVRENGIYMLRENEISGGKHKANGKVHEVSGKTGNS 165
                                         :|:...:.|...:::.  |.::.|..:        :
plant   144 LAQGASACAVDIEEAANQPGQLTNSGPSIKVKHRAVQMRNTSKLQ--KEESRGNAY--------N 198

  Fly   166 LLTFSAQCNFSGYKIPLEVIEQIQIDGLAKPGKE--LWSSLGEKKKNMHNDYYICLDAASFVATS 228
            |..|.::|||||.:..|::::      |.|...|  |..|...|.|.    :.:.:|||...||.
plant   199 LFAFPSECNFSGLRFNLDLVK------LMKENTETVLQGSPFSKSKR----WMVLIDAAKGCATL 253

  Fly   229 PLDLQKYRPDYVCLSFYKIFGYPTGVGALLVSRRGAEVFQKRRFFGGGTINYAYPHAMDYQLRET 293
            |.||.:|..|:|.|||||:||||||:||||| |..|....|:.:|.|||:..:.......:.||.
plant   254 PPDLSEYPADFVVLSFYKLFGYPTGLGALLV-RNDAAKLLKKTYFSGGTVAASIADIDFVKRRER 317

  Fly   294 FHQRYEDGTLPFLSIVGLLEGFRTLERLVPRTDEFSTMERISRHVFGLAKYLEDQLRQLHHPNGE 358
            ..:.:|||:..||||..:..||:.|:.|.|        ..|..|...|:.|::.:|:.|.|.||.
plant   318 VEEFFEDGSASFLSIAAIRHGFKLLKSLTP--------SAIWMHTTSLSIYVKKKLQALRHGNGA 374

  Fly   359 PLVKLYNKVGYQDKSRQGG-IVAFNVRTESGSFVGFGEIACVAALHGILLRTGCFCNIGACQYYL 422
            .:..||.....:..|.:.| .|.||::...||:.|:.|:..:|:|.||.||||||||.|||..||
plant   375 AVCVLYGSENLELSSHKSGPTVTFNLKRPDGSWFGYLEVEKLASLSGIQLRTGCFCNPGACAKYL 439

  Fly   423 GLDEDALDAIYKRAGRICGDYFDLIDGQPTGAVRVSFGYMTTIQDVDKLLQMLRSSYLA-TKPLQ 486
            .|....|.:..: ||.||.|..|:|:|:||||||||||||:|.:|..|.:..:.||:.: .|...
plant   440 ELSHSELRSNVE-AGHICWDDNDVINGKPTGAVRVSFGYMSTFEDAKKFIDFIISSFASPPKKTG 503

  Fly   487 RIQFIEEQAEQLPPL-LKERVQLLRPKLLQMAIYPVKSCAAFKIELPGSWPLTDQGLKYDREWMI 550
            ....:..:..|||.. |:.:.......|..:.:||:||||.|.:.   .|||...||.:|||||:
plant   504 NGTVVSGRFPQLPSEDLESKESFPSHYLKSITVYPIKSCAGFSVI---RWPLCRTGLLHDREWMV 565

  Fly   551 VDMNGMALTQKRCTELCLIRPVIKV-------------DQLELQFGENSTISVPLSLDDQAADTA 602
            ..:.|..||||:..|:.||:..|.:             |:|.::...:|........|..|...|
plant   566 QGLTGEILTQKKVPEMSLIKTFIDLEEGLLSVESSRCEDKLHIRIKSDSYNPRNDEFDSHANMYA 630

  Fly   603 K-----CVSKV--------CRQPVEGLDCGDRVAQWLSENLGMEGLRLLRQSGQRNSSKD----- 649
            .     |::..        ||  :|..:...|:.:|.:..:|.: .:|||.|.  ::|||
plant   631 LLLIMCCLTSAACNKFDFGCR--LENRNEETRINRWFTNAIGRQ-CKLLRYSS--STSKDCLNRN 690

  Fly   650 ---------QQKLSLVNQAQFLLLNKSSVRSLQFE-EPLDE---------TVDRFRANIIIDTGS 695
                     :..::..|:|||||:::.||..|... |..||         ...|||.|::|..|.
plant   691 KSPGLCRDLESNINFANEAQFLLISEESVADLNRRLEAKDEDYKRAHEKLNPHRFRPNLVISGGE 755

  Fly   696 AFEELTYKALSIGGIQFQVEGPCQRCDMICINQRTG--ERSPETLTTIS--RLQKGRMRFGIYIT 756
            .:.|..:|.:.||...|...|.|.||.||.|:...|  ::|.|.|||::  |..||::.||..:
plant   756 PYGEDKWKTVKIGDNHFTSLGGCNRCQMINISNEAGLVKKSNEPLTTLASYRRVKGKILFGTLL- 819

  Fly   757 RIPQDTKELEPKEQ 770
                 ..|::.|.|
plant   820 -----RYEIDEKRQ 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mal	NP_001285493.1	PLN02724	17..753	CDD:215384	276/829 (33%)
		AAT_I	29..475	CDD:302748	177/483 (37%)
		MOSC_N	511..633	CDD:281474	40/147 (27%)
		MOSC	651..754	CDD:281471	41/116 (35%)
ABA3	NP_001322902.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I942
eggNOG	1	0.900	-	-		E1_COG0520
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9931
Inparanoid	1	1.050	377	1.000	Inparanoid score	I543
OMA	1	1.010	-	-		QHG55229
OrthoDB	1	1.010	-	-		D394559at2759
OrthoFinder	1	1.000	-	-		FOG0006590
OrthoInspector	1	1.000	-	-		oto3927
orthoMCL	1	0.900	-	-		OOG6_102414
Panther	1	1.100	-	-	LDO	PTHR14237
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4833
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840