Protein Alignment mal and Mocos

DIOPT Version :10

• Sequence 1: NP_523423.1
• Gene: mal / 33045
• FlyBaseID: FBgn0002641
• Length: 781
• Species: Drosophila melanogaster
• Sequence 2: NP_081055.1
• Gene: Mocos / 68591
• MGIID: 1915841
• Length: 862
• Species: Mus musculus
• Alignment Length: 844
• Identity: 318/844 - (37%)
• Similarity: 456/844 - (54%)
• Gaps: 155/844 - (18%)

  Fly    17 DAEFSRLASNKSVYLDHAGTTLYAESQVTAAAEQLQRNVICNPH----TCRLTGDFVDQVRFKIL 77
            |.||.|||.  :|||||||.||:.:||:|...:.|..||..|||    |.:||.|.|:|||::||
Mouse    40 DQEFGRLAG--TVYLDHAGATLFPQSQLTNFTKDLMENVYGNPHSQNITSKLTHDTVEQVRYRIL 102

  Fly    78 EFFNTTAEDYHVIFTANATAALSLVAENFDFGS-----SGEFHFC--QENHTSVLGMRE---RVR 132
            ..|:||.|||.|||||.:||||.||||.|.:.|     ||. |||  .:|||||:|||:   .:.
Mouse   103 THFHTTPEDYIVIFTAGSTAALRLVAEAFPWVSRSPENSGS-HFCYLTDNHTSVVGMRKVAAAMS 166

  Fly   133 ENGIYMLRENEISGGKHKANGKVHEVSGKTGNS---------LLTFSAQCNFSGYKIPLEVIEQI 188
            ...|.:..|:            :....||...:         |..:.||.||||.:.||..:|::
Mouse   167 VTSIPVKPED------------MWSAEGKDAGACDPDCQLPHLFCYPAQSNFSGTRYPLSWVEEV 219

  Fly   189 QIDGLAKPGKELWSSLGEKKKNMHNDYYICLDAASFVATSPLDLQKYRPDYVCLSFYKIFGYPTG 253
                  |.|:       ....|....:::.|||||:|:||||||..::.|::.:|||||||.|||
Mouse   220 ------KSGR-------RSPVNAPGKWFVLLDAASYVSTSPLDLSAHQADFIPISFYKIFGLPTG 271

  Fly   254 VGALLVSRRGAEVFQKRRFFGGGTINYAYPHAMDYQL-RETFHQRYEDGTLPFLSIVGLLEGFRT 317
            :|||||::..|.:.:| .:|||||. .||....|:.: |.:..:|:||||:.||.::.|..||..
Mouse   272 LGALLVNKHVAPLLRK-GYFGGGTA-AAYLAGEDFYVPRSSVAERFEDGTISFLDVIALKHGFDA 334

  Fly   318 LERLVPRTDEFSTMERISRHVFGLAKYLEDQLRQLHHPNGEPLVKLYNKVGYQDKSRQGGIVAFN 382
            ||.|.      ..|..|.:|.|.|.:|....|..|.:.||.|:|::|:...:.....||.|:.||
Mouse   335 LEHLT------GGMVNIQQHTFALVQYTHSALSSLRYLNGAPVVRIYSDSEFSSPDVQGPIINFN 393

  Fly   383 VRTESGSFVGFGEIACVAALHGILLRTGCFCNIGACQYYLGLDEDALDAIYKRAGRICGDYFDLI 447
            |..:.|..:|:.::..:|:|:.|.||||||||:||||.:|||.::.:...: :||.:|||..|:|
Mouse   394 VLDDGGKIIGYSQVDKMASLYNIHLRTGCFCNLGACQRHLGLSDEMVKKHF-QAGHVCGDDVDII 457

  Fly   448 DGQPTGAVRVSFGYMTTIQDVDKLLQMLRSSYL---ATKPLQRIQFIEEQA-------------- 495
            ||:|||:||:|||||:|::|....|:.:.:.||   :.:|:.:....:..|
Mouse   458 DGRPTGSVRISFGYMSTLEDAQAFLRFISTIYLRSPSDQPVPQASISDAGALTSKSDCHSPQEGS 522

  Fly   496 -----------------EQLPPLLKERVQLLRPK---------------LLQMAIYPVKSCAAFK 528
                             :..|.|.|.......|:               :..:.:||:||||||:
Mouse   523 CTDPSVCNGSYPDTNIMDLHPSLSKASSAQQTPQDKAAGILNGDPGSHIVTNIYLYPIKSCAAFE 587

  Fly   529 IELPGSWPLTDQGLKYDREWMIVDMNGMALTQKRCTELCLIRP---------VIKVDQLELQFGE 584
            :.   .||:..|||.|||.||:|:.||:.::||:...||||:|         |||.:.:|
Mouse   588 VT---KWPVGSQGLLYDRSWMVVNHNGICMSQKQEPRLCLIQPFIDLQQRIMVIKAEGME----- 644

  Fly   585 NSTISVPLSLDDQAADTAKCVSKVCRQPVEGLDCGDRVAQWLSENLGMEGLRLLRQSG--QRNSS 647
              .|.|||..|.:  .|..|.|:||...|...|||:.|::|||:.|| ....|::||.  |||:.
Mouse   645 --PIQVPLEEDGE--QTQICQSRVCADRVNTYDCGENVSRWLSKFLG-RLCHLIKQSPHFQRNAR 704

  Fly   648 KDQQK---------LSLVNQAQFLLLNKSSVRSLQ----------FEE--PLDETVDRFRANIII 691
            |..:|         |||||:||:||:|.||:..||          .||  .:.:.:.|||||||.
Mouse   705 KTPKKGQPPGTTVALSLVNEAQYLLVNTSSILELQRQLNASDEHGKEESFSMKDLISRFRANIIT 769

  Fly   692 DTGSAFEELTYKALSIGGIQFQVEGPCQRCDMICINQRTGERSPETLTTISRLQKGRMRFGIYI 755
            ....||||..:..:|||.:.|||.|||.||.||||||:||:|:.:...|:|..:..::.||:|:
Mouse   770 KGARAFEEEKWDEISIGSLHFQVLGPCHRCQMICINQQTGQRNQDVFQTLSESRGRKVNFGVYL 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mal	NP_523423.1	PLN02724	17..753	CDD:215384	316/840 (38%)
Mocos	NP_081055.1	PLN02724	28..854	CDD:215384	318/844 (38%)