Protein Alignment mal and Y71H2B.5

DIOPT Version :10

• Sequence 1: NP_523423.1
• Gene: mal / 33045
• FlyBaseID: FBgn0002641
• Length: 781
• Species: Drosophila melanogaster
• Sequence 2: NP_497589.3
• Gene: Y71H2B.5 / 175380
• WormBaseID: WBGene00022195
• Length: 957
• Species: Caenorhabditis elegans
• Alignment Length: 771
• Identity: 167/771 - (21%)
• Similarity: 272/771 - (35%)
• Gaps: 238/771 - (30%)

  Fly     8 FSASEQSQIDAEFS-RLASNKSVYLDHAGTTLY--AESQVTAAAEQLQRNVICNPHTCRLTGDFV 69
            |.|.:.:..|...| |..::...|:.|.....|  ..|.||..|||              |..|:
 Worm    55 FGARKVTYCDYTASARAFTSIETYIQHEVLPFYGNTHSSVTVTAEQ--------------TTLFM 105

  Fly    70 DQVRFKILEFFNTTAEDYHVIFT-ANATAALSLVAENFDFGSSGE----FHFCQENHTSVLGMRE 129
            .:.|.:|..|.....:| .|||| :.:|.|:.|:......|...|    .|..||:|:::|..|:
 Worm   106 HEARQEIRAFSGCGDQD-SVIFTGSGSTCAVELLVHLMSDGKDDEEVIVVHSSQEHHSNLLPWRK 169

  Fly   130 RVR--------ENG----IYM---LRENEISGGKHKANGKVHEVSGKTGNSLLTFSAQCNFSGYK 179
            ..:        |||    :::   |:|...|.|..|..|              ||.|..|.:|..
 Worm   170 IAKECRNIEELENGQIDLVHLQNVLKEIRESHGSIKIIG--------------TFCAASNLTGIL 220

  Fly   180 IPLEVIEQI--QIDGLAKPGKELWSSLGEKKKNMHNDYYICLDAASFV-----ATSPLDLQKYRP 237
            |.::.:.:|  ..|.:|     :|            |:   ..||.::     .|.|||.
 Worm   221 IDIQNVTKILKMFDAIA-----IW------------DF---ASAAPYIPILVNGTYPLDA----- 260

  Fly   238 DYVCLSFYKIFGYPTGVGALLVSRRGAEVFQKRRFFGGGTINYAYPHAMD-YQLRETFHQRYEDG 301
              |..|.:|..|..:..|.|:|.:...:..:.:| .||||:.:.  ::.| :.|:|..| |.|.|
 Worm   261 --VFFSGHKFPGGVSSPGVLIVKKSIIQATKPKR-IGGGTVFFV--NSTDEWYLKEVEH-REEGG 319

  Fly   302 TLPFLSIVGLLEGFRTLERLVPRTDEFSTMERISRHVFGLAKYLEDQLRQLHHPNGEPLVKLYNK 366
            |...:..|.|....: ::|.:.. |....:|....|:      :..::|.:     |.||.|
 Worm   320 TADAVGAVRLAMAVK-MKRSIGE-DTIKNLESSISHL------VLQKIRTI-----ENLVLL--- 368

  Fly   367 VGYQDKSRQGGIVAFNVR-TESGSFVGFGEIACVA-ALHGILLRTGCFCNIGACQYYLGLDEDA- 428
             |......:..:.:|.:| .:|..|.....|:.:. .|.||..|.||.|.....|..||:||:.
 Worm   369 -GPSVVDHRLPVFSFLIRDPQSQLFFHHNYISVLLNDLFGIQTRAGCMCAGPYSQKLLGIDEELS 432

  Fly   429 ------------LDAIYKRAGRICGDYFDLIDGQPTGAVRVSFGYMTTIQDVDKLLQMLRSSYLA 481
                        ||..:.|..   .:|......:| |..|:||.|...:.:||::|:.:|
 Worm   433 QRFVSAIQESPDLDRTHLRRQ---AEYSQQEFLRP-GFTRISFPYFFKMAEVDEILEAIR----- 488

  Fly   482 TKPLQRIQFIEEQAEQLPPLLKERVQLLRPKLLQMAIYPVKSCAAFKIELPGSWPLTDQGLKYDR 546
                    ||.:.|...                 :.:|.| :|..      |.|...:|.:.:.|
 Worm   489 --------FIAKHAADF-----------------LHLYQV-NCET------GEWHHQNQRVFHGR 521

  Fly   547 EWMIVDMNGMALTQKRCTELCLIRPVIKVDQLELQFGENSTISVPLSLDDQAADTAKCVSKVCRQ 611
            .|:     |                       .:||......:.||:: .:..|..||
 Worm   522 RWL-----G-----------------------HVQFTPTGLKTKPLAV-PEVPDMKKC------- 550

  Fly   612 PVEGLDCGDRVAQWLSENLGMEGLRLLRQSGQRNSSKDQQKLSLVNQAQFLLLNKSSVRSLQFEE 676
                                :|..::|.|     .|.|...:|.:...: |.:|........|..
 Worm   551 --------------------LEAAKVLAQ-----ESSDALNISKIPDGR-LAINSEYHELRWFVL 589

  Fly   677 PLDETVDRFRAN-------IIIDTGSAFEELTYKALSIGGIQFQVEGPCQRCDMIC 725
            |::  |...||.       .:|......||.:::  .|...|.| |.|.:.|::||
 Worm   590 PIE--VAEARAGRAVSFPMCVIKPRKYTEEASHQ--EIPSEQHQ-EAPQEECEVIC 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mal	NP_523423.1	PLN02724	17..753	CDD:215384	165/762 (22%)
Y71H2B.5	NP_497589.3	CsdA	54..493	CDD:440286	126/531 (24%)
		TtcA-like	712..901	CDD:467514