Protein Alignment cactin and cactin

DIOPT Version :10

• Sequence 1: NP_523422.4
• Gene: cactin / 33043
• FlyBaseID: FBgn0031114
• Length: 720
• Species: Drosophila melanogaster
• Sequence 2: XP_316580.5
• Gene: cactin / 1277141
• VectorBaseID: AGAMI1_011832
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 571
• Identity: 335/571 - (58%)
• Similarity: 409/571 - (71%)
• Gaps: 56/571 - (9%)

  Fly   177 SNLTSTFHWGKKLEVEGLSNLSTKTVEVLSLQKQLENRRELEKVKKRRQERELERQVREDDLMMQ 241
            |..::.|.|.||||.:||.::|.:.:|.|:.:.||||..||||:||||.|||.::|.||||:.:.
Mosquito     6 SEKSAPFVWKKKLEKQGLKDISRRELEALNRKTQLENVIELEKIKKRRLEREHQQQQREDDMYLM 70

  Fly   242 QRAKEAVQFREWQRQEDQFHLEQARLRSEIRIRDGRAKPIDLLAQYVAAGNEPLEECLEMQMHEP 306
            ||:|||.||.||||||:.||||||:|||:|||:|||||||||||||::..|  |||.:|||||||
Mosquito    71 QRSKEAAQFDEWQRQEETFHLEQAKLRSKIRIQDGRAKPIDLLAQYISEQN--LEESIEMQMHEP 133

  Fly   307 YVLLNGLPVEELEDLLVDIKVYEELEQGKHIDFWNDMITIVQDELQRQQKLEAENSSLNQ-RRDG 370
            |..||||.:::|||||||||||.|||:||::|||.|:..||.||:.:.:|:|||...:.. ||:|
Mosquito   134 YTYLNGLGLDDLEDLLVDIKVYNELEKGKNLDFWTDLTIIVDDEIHKLRKVEAEKQRIAAGRREG 198

  Fly   371 IHQAVVKDVADIFRGKNAQQLEEMRHRIEAKISGRADGVDISYWESLLSQLKAHMARARLRDRHQ 435
            |||:|.|||..|||||.|||||:::.:||.||..:.||:||.|||||||||||||||||||||||
Mosquito   199 IHQSVAKDVTQIFRGKTAQQLEDLKKKIEEKIGSQQDGLDIGYWESLLSQLKAHMARARLRDRHQ 263

  Fly   436 ALLREKLSLLKRENDNETLQEKVAPQVKEEEMETQDAEDP----EVEEGSPED------------ 484
            ..||.||.|||:|.:.         |||:|.....|...|    :|::.|..|
Mosquito   264 ENLRSKLELLKQEQEQ---------QVKKEVQSEDDEAGPSGLGQVDDSSSRDSAAVQSESEAAG 319

  Fly   485 ---------EEDPLNELRKTVRLYQAGNYSPRYIREEDFTGRRAQNEDVDEPEAEGLLYEEEDDE 540
                     |.|.|||   ....|:.|.|.|:|::..|.           ||..| ::.|::|:|
Mosquito   320 PSKPTQDTYESDLLNE---CFEQYKKGGYEPKYLQPGDL-----------EPGIE-IITEDKDEE 369

  Fly   541 -RRTQRQRLLILHPERVDNNQLTPQELRMRNEAKQGMQGDEAEFSVETTLDAVPQLATDKYRPRK 604
             ....||::|.::.   |....:.:|:.:|.||::||..|||||||||.:|:...|.:|||||||
Mosquito   370 ILDLLRQKVLGINQ---DEELYSREEMLLRKEARRGMDNDEAEFSVETRVDSQVYLWSDKYRPRK 431

  Fly   605 PRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLMDKSQTPQYFLTPCADNGDFAV 669
            |||||||||||||||||||||||||||||||||||||||||||::|:.|||||||||:||||||.
Mosquito   432 PRYFNRVHTGFEWNKYNQTHYDMDNPPPKIVQGYKFNIFYPDLINKNTTPQYFLTPCSDNGDFAT 496

  Fly   670 LRFHTGPPYEDIAFKIVNREWEFSYKRGFRCQFHNNIFQLWFHFKRYRYRR 720
            ||||.||||||||||||||||||||||||||||.|||||||||||||||||
Mosquito   497 LRFHAGPPYEDIAFKIVNREWEFSYKRGFRCQFQNNIFQLWFHFKRYRYRR 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cactin	NP_523422.4	Smc	<109..>540	CDD:440809	198/388 (51%)
		Cactin_mid	243..434	CDD:463049	129/191 (68%)
		CactinC_cactus	598..720	CDD:401611	113/121 (93%)
cactin	XP_316580.5	None