| Sequence 1: | NP_608388.2 | Gene: | HERC2 / 33035 | FlyBaseID: | FBgn0031107 | Length: | 4912 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055421.1 | Gene: | HERC3 / 8916 | HGNCID: | 4876 | Length: | 1050 | Species: | Homo sapiens |
| Alignment Length: | 1086 | Identity: | 250/1086 - (23%) |
|---|---|---|---|
| Similarity: | 407/1086 - (37%) | Gaps: | 314/1086 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4054 WGHNHRGQLG---GLEGSRIKTPTPCEALSLLRPVQLA-GGEQSLFAVTPDGKLFATGYGSGGRL 4114
Fly 4115 G---VGGSDSWAIPTLLGSL--QHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLG-HGNR 4173
Fly 4174 MSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHG-DSEDQLRPKLVEAL 4237
Fly 4238 LGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLPYKIESLAGLGVVKVECG 4302
Fly 4303 SQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVA-CSDSGE 4366
Fly 4367 VYTWGDNDEGQLGDGTVTAIQRPRLV----AALQGK----------HIVK----------VTC-- 4405
Fly 4406 -------------GSAH--------TLALSTSQLS------------------------------ 4419
Fly 4420 -ERLRPLPNPP-----------------------------LEYDLVRDLAP-----EALHARLIL 4449
Fly 4450 ---------------------------------LHHFSELVCPCLAM------------------ 4463
Fly 4464 ---LPI-SGDLSLGALK---------------------------------DVLVYNIKEAAFR-- 4489
Fly 4490 -KVIQTTM-------VRDKQ-HGPVIELN-RIQVKRSRNRCNGLAGIDGMKSVFGQMVQKLPLLT 4544
Fly 4545 QEALALPH-----------------------RVWKVKFVGESVDDCGGGYSESIAEMCDELQNGS 4586
Fly 4587 VPLLINTPNGRGEAGANRDCFLLDPTLSSVLQMNMFRFLGVLMGIAVRTGSPLSINLAEPVWRQL 4651
Fly 4652 TG--------EVLRPT------DLTEVDRDYVAGLLCIRNMDDDPKLFTALELPFSTSSARGHEV 4702
Fly 4703 PLSTRYTHISPRNRAE----YVRLALGFRLHEFDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMV 4763
Fly 4764 CGSPDIPLGLLKSVATYKG-FDPSSALVTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRG 4827
Fly 4828 RDFVLQVLEKNPPDHFLPESYTCFFLLKMPRYSCKAVLLEKLKYAI 4873 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HERC2 | NP_608388.2 | RCC1 | 638..683 | CDD:278826 | |
| RCC1 | 687..737 | CDD:278826 | |||
| RCC1 | 740..787 | CDD:278826 | |||
| RCC1 | 790..841 | CDD:278826 | |||
| RCC1_2 | 828..857 | CDD:290274 | |||
| Cyt-b5 | 1290..1363 | CDD:278597 | |||
| MIB_HERC2 | 1928..1987 | CDD:284184 | |||
| UBA_HERC2 | 2515..2559 | CDD:270585 | |||
| Cul7 | 2624..2699 | CDD:288381 | |||
| APC10-HERC2 | 2762..2932 | CDD:176485 | |||
| RCC1 | 3037..3088 | CDD:278826 | |||
| RCC1 | 3091..3140 | CDD:278826 | |||
| RCC1 | 3144..3194 | CDD:278826 | |||
| RCC1 | 3197..3246 | CDD:278826 | |||
| RCC1 | 3250..3298 | CDD:278826 | |||
| RCC1 | 3302..3350 | CDD:278826 | |||
| RCC1_2 | 4136..4166 | CDD:290274 | 10/29 (34%) | ||
| RCC1 | 4154..4203 | CDD:278826 | 16/49 (33%) | ||
| RCC1 | 4206..4257 | CDD:278826 | 17/51 (33%) | ||
| RCC1 | 4260..4309 | CDD:278826 | 12/48 (25%) | ||
| RCC1 | 4312..4360 | CDD:278826 | 18/47 (38%) | ||
| RCC1 | 4364..4413 | CDD:278826 | 23/95 (24%) | ||
| HECTc | 4509..4880 | CDD:238033 | 94/408 (23%) | ||
| HECTc | 4553..4878 | CDD:214523 | 85/340 (25%) | ||
| HERC3 | NP_055421.1 | RCC1 1 | 1..51 | 15/48 (31%) | |
| ATS1 | 2..331 | CDD:227511 | 110/339 (32%) | ||
| RCC1 2 | 52..101 | 18/57 (32%) | |||
| RCC1 3 | 102..154 | 17/51 (33%) | |||
| RCC1 4 | 156..207 | 17/52 (33%) | |||
| RCC1 5 | 208..259 | 13/50 (26%) | |||
| RCC1 6 | 261..311 | 18/49 (37%) | |||
| RCC1 | 313..377 | CDD:366085 | 18/63 (29%) | ||
| RCC1 7 | 313..366 | 17/52 (33%) | |||
| HECTc | 702..1048 | CDD:238033 | 86/367 (23%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1062377at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||