Protein Alignment HERC2 and rccd1

DIOPT Version :10

• Sequence 1: NP_608388.2
• Gene: HERC2 / 33035
• FlyBaseID: FBgn0031107
• Length: 4912
• Species: Drosophila melanogaster
• Sequence 2: XP_073798700.1
• Gene: rccd1 / 567613
• ZFINID: ZDB-GENE-030131-3552
• Length: 376
• Species: Danio rerio
• Alignment Length: 301
• Identity: 90/301 - (29%)
• Similarity: 123/301 - (40%)
• Gaps: 92/301 - (30%)

  Fly  3053 LGVTHNVPLP--------HQLPVLRQYVVKKVAVHSGGKHALALTLDGKVFSWGEGEDGKLGHGN 3109
            |...|...||        |:.|......:..|::..|.:|||.||.||.::|||.|..|:||||.
Zfish   125 LSAEHTAALPLVSGGFVQHKPPFFHPLKLCAVSLVLGSEHALLLTADGTLYSWGSGSHGQLGHGA 189

  Fly  3110 RTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLGEYGRLGHGDNTTQLKPKLVTAL 3174
            .|:|:.|:.||||....|:.||.|:.||||:||.|:||.||..|.|:||               |
Zfish   190 LTSLEDPQAVEALWGVPIKAVAAGNWHSAAVSSGGDLYMWGWNESGQLG---------------L 239

  Fly  3175 AGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSEGSDTPHEIERLSGIGVV----- 3234
            ..|               .|.|:            |....||...|.|...:..|...|.
Zfish   240 PSR---------------GLEEE------------KRRGNGSGNDDQPMNTDEKSQTDVFISIQA 277

  Fly  3235 --------------QIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRGRRV 3285
                          :|.||::.:.|:|.||:::|||.|.|.:||||.:....:|.|:...
Zfish   278 FPALVDIANMSEISRISCGSRHTAAVTSAGDLYTWGWGQYGQLGHGTEHSTDEPTPVDYF----- 337

  Fly  3286 IHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKP 3326
                  :.|.|:|.|.            ..||.||||:..|
Zfish   338 ------SSHSLSVKDV------------VCGSWNTFVSVVP 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HERC2	NP_608388.2	ATS1	625..>894	CDD:444065
		Cyt-b5	1292..1364	CDD:459698
		MIB_HERC2	1928..1988	CDD:461991
		UBA_HERC2	2515..2559	CDD:270585
		Cul7	2624..2699	CDD:463286
		APC10-HERC2	2762..2932	CDD:176485
		ATS1	2987..3320	CDD:444065	85/293 (29%)
		RCC1	3302..3350	CDD:395335	7/25 (28%)
		ATS1	4050..4389	CDD:444065
		HECTc	4509..4880	CDD:238033
rccd1	XP_073798700.1	None