| Sequence 1: | NP_608388.2 | Gene: | HERC2 / 33035 | FlyBaseID: | FBgn0031107 | Length: | 4912 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001129676.1 | Gene: | RCC2 / 55920 | HGNCID: | 30297 | Length: | 522 | Species: | Homo sapiens |
| Alignment Length: | 415 | Identity: | 116/415 - (27%) |
|---|---|---|---|
| Similarity: | 185/415 - (44%) | Gaps: | 72/415 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4054 WGHNHRGQLGGLEGSRIKTPT--PCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGV 4116
Fly 4117 GGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNRM-SYDRPK 4180
Fly 4181 LVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHG------------DSEDQLRPKL 4233
Fly 4234 VEALL------------GYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGGSDGCKLP- 4285
Fly 4286 -YKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKII 4349
Fly 4350 SIATGSLHCVACSDSGEVYTWGDNDE-GQLGDG-----TVTAIQRPRLVAALQGKHIVKVTCGSA 4408
Fly 4409 HTLALSTSQL---SERLRPLP--NP 4428 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HERC2 | NP_608388.2 | RCC1 | 638..683 | CDD:278826 | |
| RCC1 | 687..737 | CDD:278826 | |||
| RCC1 | 740..787 | CDD:278826 | |||
| RCC1 | 790..841 | CDD:278826 | |||
| RCC1_2 | 828..857 | CDD:290274 | |||
| Cyt-b5 | 1290..1363 | CDD:278597 | |||
| MIB_HERC2 | 1928..1987 | CDD:284184 | |||
| UBA_HERC2 | 2515..2559 | CDD:270585 | |||
| Cul7 | 2624..2699 | CDD:288381 | |||
| APC10-HERC2 | 2762..2932 | CDD:176485 | |||
| RCC1 | 3037..3088 | CDD:278826 | |||
| RCC1 | 3091..3140 | CDD:278826 | |||
| RCC1 | 3144..3194 | CDD:278826 | |||
| RCC1 | 3197..3246 | CDD:278826 | |||
| RCC1 | 3250..3298 | CDD:278826 | |||
| RCC1 | 3302..3350 | CDD:278826 | |||
| RCC1_2 | 4136..4166 | CDD:290274 | 12/29 (41%) | ||
| RCC1 | 4154..4203 | CDD:278826 | 17/49 (35%) | ||
| RCC1 | 4206..4257 | CDD:278826 | 16/74 (22%) | ||
| RCC1 | 4260..4309 | CDD:278826 | 15/50 (30%) | ||
| RCC1 | 4312..4360 | CDD:278826 | 13/47 (28%) | ||
| RCC1 | 4364..4413 | CDD:278826 | 16/54 (30%) | ||
| HECTc | 4509..4880 | CDD:238033 | |||
| HECTc | 4553..4878 | CDD:214523 | |||
| RCC2 | NP_001129676.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..83 | ||
| RCC1 1 | 103..165 | 12/44 (27%) | |||
| ATS1 | <151..481 | CDD:227511 | 99/358 (28%) | ||
| RCC1 2 | 168..219 | 18/52 (35%) | |||
| RCC1 3 | 221..271 | 17/50 (34%) | |||
| RCC1 4 | 273..347 | 16/75 (21%) | |||
| Required for interaction with RAC1. /evidence=ECO:0000269|PubMed:28869598 | 318..325 | 0/6 (0%) | |||
| RCC1 5 | 348..401 | 16/52 (31%) | |||
| RCC1 6 | 403..447 | 13/49 (27%) | |||
| RCC1 7 | 448..501 | 16/56 (29%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 502..522 | 5/18 (28%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5184 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1062377at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||