Sequence 1: | NP_608388.2 | Gene: | HERC2 / 33035 | FlyBaseID: | FBgn0031107 | Length: | 4912 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_598552.2 | Gene: | Wwc2 / 52357 | MGIID: | 1261872 | Length: | 1187 | Species: | Mus musculus |
Alignment Length: | 1312 | Identity: | 252/1312 - (19%) |
---|---|---|---|
Similarity: | 434/1312 - (33%) | Gaps: | 402/1312 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 1475 GKSQLQLRADAFISGLAEARVSEPPV---------AAWLALTERY--------CKAHNLMWHQEF 1522
Fly 1523 ATEHPVQELERLLSAVLIRHQYLGGLVLNALETEVPPPRQLGEIIRLVHQAKWSVVRTRQQLNRS 1587
Fly 1588 YKEVCAPILERLRFLLYEVRPAISPQQR---GLRRLPILQRPPRFKMLVRRLLQELRSSRQPAKP 1649
Fly 1650 EDLLNASIQQEQ-----EKKPQSMPKQELEEQEEEETLLRRLNERQIHGEG--ELDPALMQDIVD 1707
Fly 1708 FALQDSCDVETARRAMYCQMQRYQLRLAGLQIVQQLLELHGLLDAAQYSLLNGFLGLHL---KST 1769
Fly 1770 SSGGGSTGSGSSLHVLGQLNMIS------AYQKARLLLAQSRV----LD---W------------ 1809
Fly 1810 --------------------AVRELRRLVNQEQQGH-------ARGKDSTNLGTYV--------L 1839
Fly 1840 LKRLPRARFLLSVFGLLAKELGPNELGFLINSGLLGTVLGLLAQTGGEGATGGQVHGELSILYED 1904
Fly 1905 SVLKQKSSKAQLSGPDLAKLMKIGTRIVRGADWKWGDQDGNPPG-------EGRII---SEVGED 1959
Fly 1960 GWVRVEWYTGATNSYRMGKEGQYDLQLADSALNVAS------------PTEPEREDV----SGSE 2008
Fly 2009 ASP---TSDSHPSKLLRHCAAKLLQILAVGTGLHGAQLDKDALRGMTSMFRTIIYPKPSMSNISY 2070
Fly 2071 ALGWLNLGFIRAISGDCP--RLC-----LELSTPGWLSHYL----------SLLEQPAGNEAGVY 2118
Fly 2119 RQLHCLRLLQLILAQWGAEEEPRMPALVHQLFATLGRIALHCPGDASLLPTAEGKARVLLTASHS 2183
Fly 2184 GSVAEELVALLRRLH--TLPSWNPVINSFLAQKLCVAAELLAEQSHSTALDSEQVFVLGVLGAMG 2246
Fly 2247 GHDLRPRVGLHCFHEGSHMVIASFTPKGRCLLAPGGVGSGVGFVKVQLPAVMPH-----LDHTVF 2306
Fly 2307 SLSRLPMNEMLLNAWTVLLYGPAPELRELP--SSADGRLDLALLRAQQLQMAVLHTNGVLYRHQV 2369
Fly 2370 ALRRILKQRAPGSIYASPDEPDRSDAESQQPGEQDQQLSSGSGQEPQLLIQCI-LLRATQASPVK 2433
Fly 2434 ACYSYMDLATAALNCIQS--------LATQAHQELSEGGGVPPNGRALSSPPQPTMVHGVPVYNV 2490
Fly 2491 ARKEQKPSEQVEQKSKWPAAATDAQLIGQIMEMGFTRRTVELALKQLSLQAEIMPTPEQIVQWI- 2554
Fly 2555 -LEHPDVCANTIEEDTLPLASSASSHDPEAD----------SDNECPSSNS------TTSSSTSS 2602
Fly 2603 DTVEGQPMAVSG 2614 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
HERC2 | NP_608388.2 | RCC1 | 638..683 | CDD:278826 | |
RCC1 | 687..737 | CDD:278826 | |||
RCC1 | 740..787 | CDD:278826 | |||
RCC1 | 790..841 | CDD:278826 | |||
RCC1_2 | 828..857 | CDD:290274 | |||
Cyt-b5 | 1290..1363 | CDD:278597 | |||
MIB_HERC2 | 1928..1987 | CDD:284184 | 11/68 (16%) | ||
UBA_HERC2 | 2515..2559 | CDD:270585 | 8/45 (18%) | ||
Cul7 | 2624..2699 | CDD:288381 | |||
APC10-HERC2 | 2762..2932 | CDD:176485 | |||
RCC1 | 3037..3088 | CDD:278826 | |||
RCC1 | 3091..3140 | CDD:278826 | |||
RCC1 | 3144..3194 | CDD:278826 | |||
RCC1 | 3197..3246 | CDD:278826 | |||
RCC1 | 3250..3298 | CDD:278826 | |||
RCC1 | 3302..3350 | CDD:278826 | |||
RCC1_2 | 4136..4166 | CDD:290274 | |||
RCC1 | 4154..4203 | CDD:278826 | |||
RCC1 | 4206..4257 | CDD:278826 | |||
RCC1 | 4260..4309 | CDD:278826 | |||
RCC1 | 4312..4360 | CDD:278826 | |||
RCC1 | 4364..4413 | CDD:278826 | |||
HECTc | 4509..4880 | CDD:238033 | |||
HECTc | 4553..4878 | CDD:214523 | |||
Wwc2 | NP_598552.2 | WW | 12..41 | CDD:278809 | 7/33 (21%) |
WW | 59..88 | CDD:278809 | 8/43 (19%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 438..464 | 9/27 (33%) | |||
C2_Kibra | 699..822 | CDD:176062 | 26/160 (16%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 830..849 | 5/19 (26%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 874..963 | 24/116 (21%) | |||
Phage_Nu1 | <1088..>1146 | CDD:294991 | 252/1312 (19%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |