| Sequence 1: | NP_608388.2 | Gene: | HERC2 / 33035 | FlyBaseID: | FBgn0031107 | Length: | 4912 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011530324.2 | Gene: | HERC5 / 51191 | HGNCID: | 24368 | Length: | 1100 | Species: | Homo sapiens |
| Alignment Length: | 1125 | Identity: | 261/1125 - (23%) |
|---|---|---|---|
| Similarity: | 442/1125 - (39%) | Gaps: | 271/1125 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3887 DAALPATSSSSSS-----SAAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTEL-PRAFCLE- 3944
Fly 3945 -VRKKFAEMLPSSSSNSNANPGCQSPGAS--MLNSTTSLSSSTVSNV--------SPPPGITGEQ 3998
Fly 3999 PDLHCHAHQLESTS--------------TLLHE-----DHTLFQAPHDAQLLQWLNRRPDDWALS 4044
Fly 4045 WGGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLRPVQLAGGEQSLFAVTPDGKLFATGYG 4109
Fly 4110 SGGRLGVGGS-DSWAIPTLLGSLQHVFVKKVAVNSGGKHCLALTTEGEVYAWGEGEDGKLGHGNR 4173
Fly 4174 MSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWGKGRYGRLGHGDSEDQLRPKLVEALL 4238
Fly 4239 GYRAIDIACGSGDAQTLC-ITDDDNVWSWGDGDYGKLGRGGSDG--CKLPYKIESLAGLGVVKVE 4300
Fly 4301 CGSQFSVALTKSG---AVYTWGKGDFHRLGHGSVDHVRRPKKVAALQGKKIISIATGSLHCVACS 4362
Fly 4363 DSGEVYTWGDNDEGQLGDGTVTAIQR----PRLVAALQGKHI----------VKVTCGSAHTLAL 4413
Fly 4414 STSQ---------------LSERLRPLPNPPLEYDLVRDLAPEA--LHARLILLHHFSELVCPCL 4461
Fly 4462 AMLPISGDLSLGALKDVLVYNIKEAAFRKVIQ---TTMV-------------------------- 4497
Fly 4498 -RDKQHGPVIELNRIQVKRSRN-----------RCNGLAGIDGMKSVFGQMVQKLPLLTQEALAL 4550
Fly 4551 PHRVWKVKFVGESVDDCGGGYSE----SIAEMCDELQNGSVPLLINTPNGRGEAGANRDCFLLDP 4611
Fly 4612 TLSSVLQMNMFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPTDLTEVDRDYVAGLLCIR 4676
Fly 4677 NMDDDPKLF-TALELPFSTSSARG--HEVPLSTRYTHISPRNRAEYVRLALGFRLHEFDEQVKAV 4738
Fly 4739 ----RDGMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYK-GFDPSSALVTWFWEVME 4798
Fly 4799 EFTNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEKNPPDHFLPESY---------TCFFLL 4854
Fly 4855 KMPRYSCKAVLLEKLKYAIH 4874 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HERC2 | NP_608388.2 | RCC1 | 638..683 | CDD:278826 | |
| RCC1 | 687..737 | CDD:278826 | |||
| RCC1 | 740..787 | CDD:278826 | |||
| RCC1 | 790..841 | CDD:278826 | |||
| RCC1_2 | 828..857 | CDD:290274 | |||
| Cyt-b5 | 1290..1363 | CDD:278597 | |||
| MIB_HERC2 | 1928..1987 | CDD:284184 | |||
| UBA_HERC2 | 2515..2559 | CDD:270585 | |||
| Cul7 | 2624..2699 | CDD:288381 | |||
| APC10-HERC2 | 2762..2932 | CDD:176485 | |||
| RCC1 | 3037..3088 | CDD:278826 | |||
| RCC1 | 3091..3140 | CDD:278826 | |||
| RCC1 | 3144..3194 | CDD:278826 | |||
| RCC1 | 3197..3246 | CDD:278826 | |||
| RCC1 | 3250..3298 | CDD:278826 | |||
| RCC1 | 3302..3350 | CDD:278826 | |||
| RCC1_2 | 4136..4166 | CDD:290274 | 9/29 (31%) | ||
| RCC1 | 4154..4203 | CDD:278826 | 22/48 (46%) | ||
| RCC1 | 4206..4257 | CDD:278826 | 23/51 (45%) | ||
| RCC1 | 4260..4309 | CDD:278826 | 16/50 (32%) | ||
| RCC1 | 4312..4360 | CDD:278826 | 5/50 (10%) | ||
| RCC1 | 4364..4413 | CDD:278826 | 13/62 (21%) | ||
| HECTc | 4509..4880 | CDD:238033 | 92/398 (23%) | ||
| HECTc | 4553..4878 | CDD:214523 | 82/343 (24%) | ||
| HERC5 | XP_011530324.2 | None | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1062377at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.820 | |||||