Protein Alignment Syx16 and STX7

DIOPT Version :9

• Sequence 1: NP_523420.1
• Gene: Syx16 / 33034
• FlyBaseID: FBgn0031106
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001313507.1
• Gene: STX7 / 8417
• HGNCID: 11442
• Length: 261
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 70/258 - (27%)
• Similarity: 122/258 - (47%)
• Gaps: 29/258 - (11%)

  Fly   107 SQIVSKLITSTHRHIQCVRSSIGVGSKMEQCLTVN---AVHCALLQLQELTVKFRASQNAYLLQL 168
            :|:..::.::..:..||   |:.:...:.|..|..   .:...|.|.|:.|.:.....:.|:.:.
Human    12 AQLAQRISSNIQKITQC---SVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEF 73

  Fly   169 NS-----REERSQKYFDDGGGAGAGDVFTNVE-LGEQSAENFVDSFDNFLQPPAEGKSGNGYLFE 227
            .|     .|:|.:|...|...|......||.: :..|:||...:    |:.........:|...|
Human    74 GSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKE----FVARVRASSRVSGSFPE 134

  Fly   228 DDEQAIDDHFQRPPAS--RMTQQQLLLFEEENT----RVAQHREQEVTKIVKSIYDLNDIFKDLG 286
            |..:      :|...|  ..||.|:.:.:||.|    |:...||..:.::...|.|:|:||||||
Human   135 DSSK------ERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLG 193

  Fly   287 HMVQEQGTVLDRIDYNVEQTQTRVSEGLRQLHKAEMYQRKNRK-MCVILVLAAVTFFMLLLLI 348
            .|:.|||.|:|.|:.|||..:..|.:..:||.:|..||||:|| :|:|:::..:...::.|:|
Human   194 MMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLII 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx16	NP_523420.1	SNARE_syntaxin16	261..319	CDD:277198	24/57 (42%)
STX7	NP_001313507.1	Syntaxin_2	18..119	CDD:373109	21/107 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..148		5/24 (21%)
		SNARE_syntaxin7	168..227	CDD:277228	24/58 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840