Protein Alignment Syx16 and STX12

DIOPT Version :9

• Sequence 1: NP_523420.1
• Gene: Syx16 / 33034
• FlyBaseID: FBgn0031106
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_803173.1
• Gene: STX12 / 23673
• HGNCID: 11430
• Length: 276
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 68/286 - (23%)
• Similarity: 124/286 - (43%)
• Gaps: 58/286 - (20%)

  Fly    91 PAFDDQRDDECDIEVLSQIVSKLITSTHRHIQCVRSSIGV---GSKMEQCLTVNAVHCALLQLQE 152
            |:....||....|:..|..:.::..:| ..|:.:.|.:|.   .||:::         .|.|||.
Human    14 PSGPQLRDFSSIIQTCSGNIQRISQAT-AQIKNLMSQLGTKQDSSKLQE---------NLQQLQH 68

  Fly   153 LTVKFRASQNAYLLQLNS----------REERSQKYFDDGGGAGAGDVFTNVELGEQSAENFVDS 207
            .|.:.....|..|.:|.|          |::|.||                    |:...:|..:
Human    69 STNQLAKETNELLKELGSLPLPLSTSEQRQQRLQK--------------------ERLMNDFSAA 113

  Fly   208 FDNF-----------LQPPAEGKSGNGYLFED---DEQAIDDHFQRPPASRMTQQQLLLFEEENT 258
            .:||           .:..|..::|:....|:   :||.:............:|:..:...|::.
Human   114 LNNFQAVQRRVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDL 178

  Fly   259 RVAQHREQEVTKIVKSIYDLNDIFKDLGHMVQEQGTVLDRIDYNVEQTQTRVSEGLRQLHKAEMY 323
            .:.:.||..:.::...|.|:|.|||||..|:.:||.::|.|:.|||.::..|.....||.:|..|
Human   179 ELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYY 243

  Fly   324 QRKNR-KMCVILVLAAVTFFMLLLLI 348
            |:|:| |||:::::.:|...:|.|:|
Human   244 QKKSRKKMCILVLVLSVIILILGLII 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx16	NP_523420.1	SNARE_syntaxin16	261..319	CDD:277198	21/57 (37%)
STX12	NP_803173.1	Syntaxin_2	30..132	CDD:373109	24/131 (18%)
		SNARE_syntaxin12	181..247	CDD:277229	24/65 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840