DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx16 and syx-16

DIOPT Version :9

Sequence 1:	NP_523420.1	Gene:	Syx16 / 33034	FlyBaseID:	FBgn0031106	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_001379771.1	Gene:	syx-16 / 175712	WormBaseID:	WBGene00022534	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	361	Identity:	109/361 - (30%)
Similarity:	184/361 - (50%)	Gaps:	62/361 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TSRNLTEVFVIMRNNASKNRNHYDD------RRGSDAERLLKHSVREAEEGLELQDDYGTPPAWL 60
            |:|||||||:::|:||.::|..|.|      |...|.||:   ::.|.|:|.:..|:   .|.|:
Worm    21 TTRNLTEVFMLLRSNAHQSRLIYKDDTDIIVRSRGDEERM---ALVELEDGRQESDE---EPVWI 79

  Fly    61 DKFEEAQYTMSKIKPKLDELGSLHARHLLRPAFDDQ--RDDECDIEVLSQIVSKLITSTHRHIQC 123
            ...::.::.:.:::.:|||||....:|:.||.|.|:  ..:|..:|..::.:::::|...|.|:.
Worm    80 HTADQVEFEVERVQRRLDELGEAQRKHISRPNFGDEAFEKEEKQMEQTTEQITQMLTHCQRLIRM 144

  Fly   124 VRSSIGVGSKMEQCLTVNAVHCALLQLQELTVKFRASQNAYLLQLNSREERSQKYFDDGGGAGAG 188
            :..|......|::.|..||.....|.|.::|.:||..|..||..:.:|
Worm   145 ISGSHNKEKPMQRKLRENAAATLSLTLSQITDEFRGRQLKYLSDIQNR----------------- 192

  Fly   189 DVFTNVELGEQSAENFVDSFDNFLQPP--AEGKSGNGYLFEDDEQAIDDHFQRPPASRMTQQQLL 251
                     .::.:|::.:.|..:..|  ||                   ....|::.::..||.
Worm   193 ---------SRNVDNYLITTDPLIDAPNWAE-------------------LDVSPSTEISMAQLQ 229

  Fly   252 LFEEENTRVAQHREQEVTKIVKSIYDLNDIFKDLGHMVQEQGTVLDRIDYNVEQTQTRVSEGLRQ 316
            .| ..|.|..:.||:||..:..||.:||.:|:||..|:.:||:|:||||||||||..|||:.:..
Worm   230 QF-MNNDREVREREKEVMAVNTSIRELNTLFQDLSEMIVDQGSVIDRIDYNVEQTSIRVSKAVED 293

  Fly   317 LHKAEMYQRKNRKMCVILVLAAVTFFMLLLLILTKL 352
            :.|||.||:.|:||..|.:|.....|:|:|:|:|||
Worm   294 VFKAERYQKGNKKMHCICMLTVAIIFVLILIIVTKL 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx16	NP_523420.1	SNARE_syntaxin16	261..319	CDD:277198	28/57 (49%)
syx-16	NP_001379771.1	COG5325	69..316	CDD:227635	81/295 (27%)
syx-16	NP_001379771.1	SNARE_syntaxin16	238..296	CDD:277198	28/57 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158855
Domainoid	1	1.000	102	1.000	Domainoid score	I4322
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2791
Inparanoid	1	1.050	163	1.000	Inparanoid score	I2833
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53593
OrthoDB	1	1.010	-	-		D1182451at2759
OrthoFinder	1	1.000	-	-		FOG0003413
OrthoInspector	1	1.000	-	-		oto18726
orthoMCL	1	0.900	-	-		OOG6_101604
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	1	1.000	-	-		X2307
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800