DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(1)G0004 and pno-1

DIOPT Version :9

Sequence 1:	NP_608387.1	Gene:	l(1)G0004 / 33033	FlyBaseID:	FBgn0027334	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_496099.1	Gene:	pno-1 / 174534	WormBaseID:	WBGene00013144	Length:	277	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	130/239 - (54%)
Similarity:	175/239 - (73%)	Gaps:	10/239 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RADAFEPAKRATKRG-ASGGGQQDVEMQVDEATGIEGQVLGSSRASAPPKAKR---ARSELRKVS 67
            :.|.|:..||..|.| |.....:||. ||||    :.....:..::.|..:||   .:.|.|.|.
Worm    44 KGDEFKLVKRKRKSGNAIDVVMEDVS-QVDE----DATADTADDSTGPKSSKRTKGVKGESRVVP 103

  Fly    68 VPPHRYSSLKEHWMKIFTPVVEHMKLQIRFNMKARQVELRVGPETPDIANLQRGADFVRAFLCGF 132
            ||.|||:.||::|:.||||:|:::.||:|||:|.||||:|...:..|..:||:..||||||:.||
Worm   104 VPKHRYTPLKDNWVNIFTPIVKNLGLQVRFNLKKRQVEIRNPVDREDTTDLQKATDFVRAFILGF 168

  Fly   133 EVDDALALLRLEDLFVESFEIKDVK-TLRGDHQSRAIGRLAGKGGRTKFTIENVTKTRIVLADSK 196
            ||:||:||:||:.||:|:||:.||| :|:|||.||||||:|||.||||..|||.||||||:|::|
Worm   169 EVNDAIALIRLDHLFLETFEVADVKHSLKGDHVSRAIGRIAGKDGRTKLVIENTTKTRIVVANTK 233

  Fly   197 IHILGSYQNIQLARRAVCNLILGSPPSKVYGNLRAVASRLSERM 240
            |||||:|||::|||.|||:|||||.||||||:||.:|||.:||:
Worm   234 IHILGAYQNLKLARNAVCSLILGSNPSKVYGSLRNMASRGAERL 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0004	NP_608387.1	Krr1	61..239	CDD:224019	112/178 (63%)
l(1)G0004	NP_608387.1	KH	165..217	CDD:197652	38/51 (75%)
pno-1	NP_496099.1	Krr1	98..276	CDD:224019	112/177 (63%)
pno-1	NP_496099.1	KH	202..254	CDD:197652	38/51 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159292
Domainoid	1	1.000	240	1.000	Domainoid score	I1257
eggNOG	1	0.900	-	-		E1_COG1094
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6961
Inparanoid	1	1.050	241	1.000	Inparanoid score	I2098
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53604
OrthoDB	1	1.010	-	-		D1269649at2759
OrthoFinder	1	1.000	-	-		FOG0005076
OrthoInspector	1	1.000	-	-		oto17998
orthoMCL	1	0.900	-	-		OOG6_101323
Panther	1	1.100	-	-	LDO	PTHR12826
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R943
SonicParanoid	1	1.000	-	-		X3599
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840