DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1504 and Gp1ba

DIOPT Version :9

Sequence 1:	NP_001259742.1	Gene:	CG1504 / 33028	FlyBaseID:	FBgn0031100	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_001103124.1	Gene:	Gp1ba / 691992	RGDID:	1310239	Length:	717	Species:	Rattus norvegicus

Alignment Length:	306	Identity:	73/306 - (23%)
Similarity:	117/306 - (38%)	Gaps:	51/306 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVLIIALSVVVCLWNSQQT-ETSKSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKN 69
            :.|:|.|.::....:||.| :.||       ..|..:|.|....|:::| ..|||....|.|:||
  Rat     1 MALLILLFLLPSPLHSQPTCDVSK-------VTSLLEVNCEDKKLKKLP-TDLPADTGILHLSKN 57

  Fly    70 NFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLS 134
            ...............|..|.|....:|.::  |...|.:|:.|.:.:..||.:.....| |..|:
  Rat    58 QLGTFSTSYLVHFTHLTHLYLSRCELTSLQ--AHEKLLKLETLDLSHNHLQSLPSLGRA-LPALT 119

  Fly   135 TILLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIRSIEQDAFF 199
            |:.:|.|::..:...|..|...::.:.|.||.|                ..||.|:.
  Rat   120 TLDVSFNKLGSLSPGALEGLGQLEELYLQNNDL----------------KSLPPGLL-------- 160

  Fly   200 GMDTVGLLKLAYMD--LKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQILNNKI 262
             |.|..||||:..:  |:|:.|....||.::..|.||.:.|..|....|..|.........|...
  Rat   161 -MPTTKLLKLSLANNKLRELPPGLLDGLEDLDTLYLQGNWLSTIPKGFFGSLLLPFVFLHANTWY 224

  Fly   263 DSIEELNFTSTAAIKHLKFFGNHVLETPDPNSIIVDGVEHLQLVSN 308
            ...|.|            :|.|.:.|.|:...:..:||:...:.:|
  Rat   225 CDCEIL------------YFRNWLQENPNRVYLWKEGVDVKAMTAN 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_001259742.1	leucine-rich repeat	61..84	CDD:275380	4/22 (18%)
		LRR_5	73..200	CDD:404228	25/126 (20%)
		leucine-rich repeat	85..108	CDD:275380	6/22 (27%)
		leucine-rich repeat	109..132	CDD:275380	6/22 (27%)
		leucine-rich repeat	133..156	CDD:275380	6/22 (27%)
		leucine-rich repeat	157..180	CDD:275380	4/22 (18%)
		leucine-rich repeat	181..203	CDD:275380	4/21 (19%)
		leucine-rich repeat	204..227	CDD:275380	9/24 (38%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	3/22 (14%)
Gp1ba	NP_001103124.1	LRRNT	20..49	CDD:214470	10/36 (28%)
		LRR_RI	<50..176	CDD:238064	35/153 (23%)
		LRR_8	51..105	CDD:290566	12/55 (22%)
		leucine-rich repeat	51..72	CDD:275380	4/20 (20%)
		leucine-rich repeat	73..94	CDD:275380	6/22 (27%)
		LRR_8	94..152	CDD:290566	15/58 (26%)
		leucine-rich repeat	95..117	CDD:275380	6/22 (27%)
		leucine-rich repeat	118..141	CDD:275380	6/22 (27%)
		LRR_8	141..198	CDD:290566	21/81 (26%)
		leucine-rich repeat	142..165	CDD:275380	9/47 (19%)
		LRR_4	164..204	CDD:289563	13/39 (33%)
		leucine-rich repeat	166..189	CDD:275380	9/22 (41%)
		leucine-rich repeat	190..211	CDD:275380	6/20 (30%)
		TPKR_C2	221..281	CDD:301599	10/50 (20%)
		TonB_N	404..523	CDD:292650
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282791at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010