DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1504 and Lrrtm2

DIOPT Version :10

Sequence 1:NP_608382.2 Gene:CG1504 / 33028 FlyBaseID:FBgn0031100 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001102939.1 Gene:Lrrtm2 / 685472 RGDID:1593785 Length:515 Species:Rattus norvegicus


Alignment Length:354 Identity:93/354 - (26%)
Similarity:155/354 - (43%) Gaps:31/354 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LVLIIALSVVVCLWNSQQTETSKSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVE---NLALT 67
            |..|.|:|||:    ........:||.:|.| .:....|::.|...:|    .||.:   .|:|.
  Rat    14 LAAIYAMSVVL----KMLPALGMACPPKCRC-EKLLFYCDSQGFHSVP----NATDKGSLGLSLR 69

  Fly    68 KNNFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQN 132
            .|:...::.|.||....|..|.||.|.|:.:|:.||:||.:||||.:....:..:....|..|.|
  Rat    70 HNHITALERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLIN 134

  Fly   133 LSTILLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSG-IRSIEQD 196
            |..:.||.||:..:....|.|...::.:.|.:|.|..|....|....::..|.|.:. :||:.::
  Rat   135 LQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 199

  Fly   197 AFFGMDTVGLLKLAYMDLKEVAPFTFRGLSNVLLLTLQESDL-GVICADAFTGLTQVETLQILNN 260
            .|.|:..:..|.|.:..|.::....|..||::..|.||.:.: .:.|...:|..| :|.|.:..|
  Rat   200 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWST-LEKLDLTGN 263

  Fly   261 KIDSIEELNFTSTAAIKHLKFFGNHVLETPDPNSIIVDGVEHLQLV---SNHFPCG---CHIHTL 319
            :|.:|:...|.:...:|.| ...|:.|.:.|  |.|:..:..|..|   .|.:.|.   |.:.:.
  Rat   264 EIKAIDLTVFETMPNLKIL-LMDNNKLNSLD--SKILSSLRSLTTVGLSGNLWECSPRVCALASW 325

  Fly   320 LDGPLAEGAHNLTDFLQKNYCISPLEVNG 348
            |........|::       .|.||....|
  Rat   326 LGSFQGRWEHSI-------LCHSPDHTQG 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1504NP_608382.2 leucine-rich repeat 61..84 CDD:275380 6/25 (24%)
LRR_5 73..200 CDD:463839 38/127 (30%)
leucine-rich repeat 85..108 CDD:275380 11/22 (50%)
leucine-rich repeat 109..132 CDD:275380 6/22 (27%)
leucine-rich repeat 133..156 CDD:275380 7/22 (32%)
leucine-rich repeat 157..180 CDD:275380 5/22 (23%)
leucine-rich repeat 181..203 CDD:275380 6/22 (27%)
leucine-rich repeat 204..227 CDD:275380 5/22 (23%)
leucine-rich repeat 228..251 CDD:275380 5/23 (22%)
leucine-rich repeat 252..275 CDD:275380 6/22 (27%)
Lrrtm2NP_001102939.1 LRR 56..>312 CDD:443914 72/263 (27%)
LRR 1 61..83 5/21 (24%)
leucine-rich repeat 66..86 CDD:275380 6/19 (32%)
LRR 2 84..107 9/22 (41%)
leucine-rich repeat 87..110 CDD:275380 11/22 (50%)
LRR 3 109..131 5/21 (24%)
leucine-rich repeat 111..134 CDD:275380 6/22 (27%)
LRR 4 132..155 8/22 (36%)
leucine-rich repeat 135..158 CDD:275380 7/22 (32%)
LRR 5 156..179 5/22 (23%)
leucine-rich repeat 159..182 CDD:275380 5/22 (23%)
LRR 6 181..203 5/21 (24%)
leucine-rich repeat 183..206 CDD:275380 6/22 (27%)
LRR 7 205..227 4/21 (19%)
leucine-rich repeat 207..230 CDD:275380 5/22 (23%)
LRR 8 229..251 5/21 (24%)
leucine-rich repeat 231..254 CDD:275380 5/22 (23%)
LRR 9 252..275 7/23 (30%)
leucine-rich repeat 255..278 CDD:275380 6/22 (27%)
LRR 10 276..299 7/25 (28%)
leucine-rich repeat 279..300 CDD:275380 7/23 (30%)
Involved in DLG4-binding 512..515
Blue background indicates that the domain is not in the aligned region.

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