Protein Alignment CG1504 and RTN4RL2

DIOPT Version :10

• Sequence 1: NP_608382.2
• Gene: CG1504 / 33028
• FlyBaseID: FBgn0031100
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_848665.1
• Gene: RTN4RL2 / 349667
• HGNCID: 23053
• Length: 420
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 87/360 - (24%)
• Similarity: 139/360 - (38%)
• Gaps: 86/360 - (23%)

  Fly     6 LVLIIALSVVVCLWNSQQTETSKSCPAECICLSQ-TQVLCNTGGLEQIPLRQLPATVENLALTKN 69
            |::::||.:           .:.|||..|.|.|. ..|.|.......:|| .||.:.:.|.|..|
Human    18 LLMLLALPL-----------AAPSCPMLCTCYSSPPTVSCQANNFSSVPL-SLPPSTQRLFLQNN 70

  Fly    70 NFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSI-QYTPLQMVAQFAFAGLQNL 133
            ....::|.:|..  .|..|.|..||::.|....||.|..|:||.: ....|:.:....|.||:.|
Human    71 LIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERL 133

  Fly   134 STILLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIRSIEQDAF 198
            .::.|...|:..:.||.|.|..:::.:.|..|.|:.:....|:.|.|:.||.| .|.|
Human   134 QSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFL-HGNR------- 190

  Fly   199 FGMDTVGLLKLAYMDLKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQILNNKID 263
                           |:.:....||||.::..|.|..:.|..:...||.||:::..|.:.||.:.
Human   191 ---------------LRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYLFNNSLA 240

  Fly   264 SIEELNFTSTAAIKHLKFFGNHVLETPDPNSIIVD--GVEHLQLVSNHFPCGCHIHTLLDGPLAE 326
            |:                          |...:.|  .:|.|:|.:|.:.|.|.
Human   241 SL--------------------------PGEALADLPSLEFLRLNANPWACDCR----------- 268

  Fly   327 GAHNLTDFLQKN-------YCISPLEVNGRVMSEL 354
             |..|..:.|:.       .|.:|.|..||.:..|
Human   269 -ARPLWAWFQRARVSSSDVTCATPPERQGRDLRAL 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_608382.2	leucine-rich repeat	61..84	CDD:275380	5/22 (23%)
		LRR_5	73..200	CDD:463839	36/127 (28%)
		leucine-rich repeat	85..108	CDD:275380	9/22 (41%)
		leucine-rich repeat	109..132	CDD:275380	7/23 (30%)
		leucine-rich repeat	133..156	CDD:275380	7/22 (32%)
		leucine-rich repeat	157..180	CDD:275380	5/22 (23%)
		leucine-rich repeat	181..203	CDD:275380	5/21 (24%)
		leucine-rich repeat	204..227	CDD:275380	5/22 (23%)
		leucine-rich repeat	228..251	CDD:275380	7/22 (32%)
		leucine-rich repeat	252..275	CDD:275380	4/22 (18%)
RTN4RL2	NP_848665.1	LRR	47..>261	CDD:443914	64/265 (24%)
		leucine-rich repeat	62..83	CDD:275380	5/22 (23%)
		leucine-rich repeat	84..107	CDD:275380	9/22 (41%)
		leucine-rich repeat	108..132	CDD:275380	7/23 (30%)
		leucine-rich repeat	133..156	CDD:275380	7/22 (32%)
		leucine-rich repeat	157..180	CDD:275380	5/22 (23%)
		leucine-rich repeat	181..204	CDD:275380	10/45 (22%)
		leucine-rich repeat	205..228	CDD:275380	7/22 (32%)
		leucine-rich repeat	229..252	CDD:275380	6/48 (13%)
		LRRCT	261..311	CDD:214507	12/54 (22%)
		PHA03247	289..>369	CDD:223021	5/14 (36%)