DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1504 and Islr2

DIOPT Version :9

Sequence 1:NP_001259742.1 Gene:CG1504 / 33028 FlyBaseID:FBgn0031100 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001155007.1 Gene:Islr2 / 320563 MGIID:2444277 Length:789 Species:Mus musculus


Alignment Length:336 Identity:64/336 - (19%)
Similarity:115/336 - (34%) Gaps:136/336 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MCNSWLVLIIALSVVVCLWNSQQTETSKSCPAECICLSQTQ---VLCNTGGLEQIPLRQLPATVE 62
            :|.:|.:|.:.                ::||..|.|:.:..   ..|....|.::| ..|||.|.
Mouse    51 LCLAWALLGVV----------------RACPEPCACVDKYAHQFADCAYKELREVP-EGLPANVT 98

  Fly    63 NLALTKNNFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAF 127
            .|:|:.|...:::                            ||                    ||
Mouse    99 TLSLSANKITVLR----------------------------RG--------------------AF 115

  Fly   128 AGLQNLSTILLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIRS 192
            ..:..::::.|:|::::.:|..|.|..|.:|.:.|::|   .|.:..:|.|              
Mouse   116 VNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDL-------------- 163

  Fly   193 IEQDAFFGMDTVGLLKLAYMDLKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQI 257
                                          |.||.:.||.:..:.||.:..||...|..:.:|:|
Mouse   164 ------------------------------RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRI 198

  Fly   258 LNNKIDSIEELNFTSTAAIKHLKFFGN--HV---------------LETPDPNSIIVDGVEHLQL 305
            .||::.::|...|.:.:|:.||:.:.|  |.               :..|:|:||.......||.
Mouse   199 NNNRLRTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQG 263

  Fly   306 VSNH----FPC 312
            |..|    .||
Mouse   264 VPVHRLPALPC 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1504NP_001259742.1 leucine-rich repeat 61..84 CDD:275380 4/22 (18%)
LRR_5 73..200 CDD:404228 16/126 (13%)
leucine-rich repeat 85..108 CDD:275380 2/22 (9%)
leucine-rich repeat 109..132 CDD:275380 2/22 (9%)
leucine-rich repeat 133..156 CDD:275380 5/22 (23%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
leucine-rich repeat 181..203 CDD:275380 0/21 (0%)
leucine-rich repeat 204..227 CDD:275380 2/22 (9%)
leucine-rich repeat 228..251 CDD:275380 7/22 (32%)
leucine-rich repeat 252..275 CDD:275380 6/22 (27%)
Islr2NP_001155007.1 leucine-rich repeat 80..96 CDD:275380 5/16 (31%)
LRR_8 96..155 CDD:290566 17/109 (16%)
leucine-rich repeat 97..120 CDD:275380 8/70 (11%)
leucine-rich repeat 121..144 CDD:275380 5/22 (23%)
LRR_4 144..183 CDD:289563 13/85 (15%)
leucine-rich repeat 145..168 CDD:275380 8/69 (12%)
LRR_8 164..227 CDD:290566 20/62 (32%)
LRR_4 169..208 CDD:289563 11/38 (29%)
leucine-rich repeat 169..192 CDD:275380 7/22 (32%)
leucine-rich repeat 193..216 CDD:275380 6/22 (27%)
LRRCT 225..273 CDD:214507 10/47 (21%)
Ig_2 288..417 CDD:290606
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D282791at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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