Protein Alignment CG1504 and LGI3

DIOPT Version :10

• Sequence 1: NP_608382.2
• Gene: CG1504 / 33028
• FlyBaseID: FBgn0031100
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_644807.1
• Gene: LGI3 / 203190
• HGNCID: 18711
• Length: 548
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 46/163 - (28%)
• Similarity: 82/163 - (50%)
• Gaps: 8/163 - (4%)

  Fly     9 IIALSVV-VCLW---NSQQTETSKSCPAECICLSQTQVLCNTGGLEQIPLRQLPATVENLALTKN 69
            ::|||.: .||.   ::::...:..||..|.|...|....::   :.:| |.||:.|.:|.|...
Human    14 LLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDS---KAVP-RNLPSEVISLTLVNA 74

  Fly    70 NFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLS 134
            .|..|:..:|:.|..|:.|.|:.|..|.|...||.||..|:.|.|:...:..:::|.|.||::|:
Human    75 AFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLT 139

  Fly   135 TILLSHNQIQRIEGNAFAGTSNIKLILLTNNPL 167
            .:.|::|.:|.:..:.|.....:..:.|..|.|
Human   140 HLSLANNNLQTLPRDIFRPLDILNDLDLRGNSL 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_608382.2	leucine-rich repeat	61..84	CDD:275380	7/22 (32%)
		LRR_5	73..200	CDD:463839	28/95 (29%)
		leucine-rich repeat	85..108	CDD:275380	10/22 (45%)
		leucine-rich repeat	109..132	CDD:275380	7/22 (32%)
		leucine-rich repeat	133..156	CDD:275380	5/22 (23%)
		leucine-rich repeat	157..180	CDD:275380	3/11 (27%)
		leucine-rich repeat	181..203	CDD:275380
		leucine-rich repeat	204..227	CDD:275380
		leucine-rich repeat	228..251	CDD:275380
		leucine-rich repeat	252..275	CDD:275380
LGI3	NP_644807.1	leucine-rich repeat	68..89	CDD:275378	6/20 (30%)
		LRR 1	89..110		8/20 (40%)
		leucine-rich repeat	90..113	CDD:275378	10/22 (45%)
		LRR	<96..247	CDD:443914	22/77 (29%)
		LRR_8	112..172	CDD:404697	14/59 (24%)
		LRR 2	113..134		5/20 (25%)
		leucine-rich repeat	114..137	CDD:275378	7/22 (32%)
		LRR 3	137..158		5/20 (25%)
		leucine-rich repeat	138..161	CDD:275378	5/22 (23%)
		leucine-rich repeat	162..174	CDD:275378	3/11 (27%)
		EAR 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	222..264
		EAR 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	268..310
		EPTP	268..308	CDD:461033
		EAR 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	314..361
		EPTP	314..359	CDD:461033
		EAR 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	363..406
		EPTP	363..404	CDD:461033
		EAR 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	410..453
		EPTP	410..451	CDD:461033
		EAR 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	455..497
		EPTP	455..495	CDD:461033
		EAR 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00075	501..543
		EPTP	501..541	CDD:461033