DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1504 and lron-13

DIOPT Version :9

Sequence 1:	NP_001259742.1	Gene:	CG1504 / 33028	FlyBaseID:	FBgn0031100	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_499798.2	Gene:	lron-13 / 190728	WormBaseID:	WBGene00013574	Length:	782	Species:	Caenorhabditis elegans

Alignment Length:	398	Identity:	85/398 - (21%)
Similarity:	151/398 - (37%)	Gaps:	100/398 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SCPAECICLSQT-QVLCNTGGLEQIPLRQLPAT-VENLALTKNNFPIIKPDSFAGLRALKKLSLD 91
            :||.:|||...: ...|.|....::.:..|.:| :.:|.:...:...::..||||:..:::||..
Worm    25 TCPRQCICHEHSIACSCETSEKPELIISSLGSTYITSLVVHTCDKVTVQNGSFAGVVLVERLSFI 89

  Fly    92 GNNITRIKQFAFRGL---PRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAG 153
            .......:..||:.:   ||  :|.|....:..:|..:||||.::..:...:::|..|...||..
Worm    90 AIGRLYFEPHAFKDILQSPR--QLVIDECTISSLAPVSFAGLSHIDHLWFRNSRIDVIATEAFHY 152

  Fly   154 TSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIR--SIEQDAFFGMDTVGLLKLAYMDLKE 216
            .:||..|......:.||:..|||.:..:.||.....|.  :||.:||.|              .:
Worm   153 LTNIDYIYFHKTKIGRIERKAFSKMYQIDHLYFKDSIEIATIESEAFSG--------------SQ 203

  Fly   217 VAPFTFRGLS-----NVLLLTLQESDLGVI--CADAFTGLTQVETLQILNNKIDS---------- 264
            |....|.|::     :..||.: |||:.::  |           ::.::..|.|.
Worm   204 VDEMIFDGVTVETAHDTFLLNV-ESDMAILKNC-----------SIYLIPRKEDDMVVFDEKQKI 256

  Fly   265 -----IEELNFTSTAAIKHLKFFGNHVLE-----------------TP--DPNSIIVDGVEHLQL 305
                 ||..:|...:..|    .|.:|||                 ||  .|...|:..:..: :
Worm   257 IERCLIESSSFNIMSPYK----LGCNVLEVTSSVIQRIGPVSRDIDTPVFRPEPFIISSLNSV-I 316

  Fly   306 VSNHFPCGCHIHTLLDGPLAEGAHNLTDFLQKNYCISPLEVNGRVMSELDIDSIGRCSDQLTKGN 370
            .||     |.|            .::..|...||.:|.|..|...:.|:...:|.:  .:::...
Worm   317 FSN-----CSI------------GSVDSFAFTNYTLSILSFNHSRIGEMKTRTIEK--SKISNFE 362

  Fly   371 LGSSAASL 378
            .|.|...|
Worm   363 FGGSTVKL 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_001259742.1	leucine-rich repeat	61..84	CDD:275380	5/22 (23%)
		LRR_5	73..200	CDD:404228	36/131 (27%)
		leucine-rich repeat	85..108	CDD:275380	4/25 (16%)
		leucine-rich repeat	109..132	CDD:275380	7/22 (32%)
		leucine-rich repeat	133..156	CDD:275380	4/22 (18%)
		leucine-rich repeat	157..180	CDD:275380	7/22 (32%)
		leucine-rich repeat	181..203	CDD:275380	8/23 (35%)
		leucine-rich repeat	204..227	CDD:275380	3/27 (11%)
		leucine-rich repeat	228..251	CDD:275380	6/24 (25%)
		leucine-rich repeat	252..275	CDD:275380	5/37 (14%)
lron-13	NP_499798.2	leucine-rich repeat	108..131	CDD:275380	9/24 (38%)
		LRR_8	111..160	CDD:290566	13/48 (27%)
		leucine-rich repeat	132..155	CDD:275380	4/22 (18%)
		leucine-rich repeat	156..179	CDD:275380	7/22 (32%)
		leucine-rich repeat	180..201	CDD:275380	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180608at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.970