Protein Alignment CG1504 and CHADL

DIOPT Version :10

• Sequence 1: NP_608382.2
• Gene: CG1504 / 33028
• FlyBaseID: FBgn0031100
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_054181131.1
• Gene: CHADL / 150356
• HGNCID: 25165
• Length: 771
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 83/400 - (20%)
• Similarity: 145/400 - (36%)
• Gaps: 114/400 - (28%)

  Fly     8 LIIALSVVVCLWNSQQTETSKSCPAECIC-LSQTQVLCNTGGLEQIPLRQLPATVENLALTKNNF 71
            |::.|.|::.|..::|. .::.||..||| .|:..|.|....|.::
Human    12 LVLPLLVLLLLAPARQA-AAQRCPQACICDNSRRHVACRYQNLTEV------------------- 56

  Fly    72 PIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTI 136
                ||:...|  .::|.|.||.:..|...||:|:|.|..|.:::..:::||:.||.||..|..:
Human    57 ----PDAIPEL--TQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLL 115

  Fly   137 LLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIRSIEQDAFFGM 201
            .|:.|.::.:...|..|..:::.:.|..|.|..:....|.:|
Human   116 NLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGAL----------------------- 157

  Fly   202 DTVGLLKLAYMDLKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQILNNKIDSIE 266
            ..:..|.||:..|..:....|:||..|..|.|..:.|.|:..:|..||..:..|.:.:|::.::.
Human   158 GALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALP 222

  Fly   267 ELNFTSTAAIKHLKFFGNHV--------LETPDPNSIIVDG------------------------ 299
            ....:....:..|:...|.:        |..|....:::||
Human   223 GPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRG 287

  Fly   300 --------------VEHLQLVSNHFPCGCHIHTLLDGPLA------EGAHNLTDFLQKNYCISPL 344
                          :..|:|..|...|||....||:. ||      :||           |..|.
Human   288 NQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEW-LARARVRSDGA-----------CQGPR 340

  Fly   345 EVNGRVMSEL 354
            .:.|..:..|
Human   341 RLRGEALDAL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_608382.2	leucine-rich repeat	61..84	CDD:275380	3/22 (14%)
		LRR_5	73..200	CDD:463839	30/126 (24%)
		leucine-rich repeat	85..108	CDD:275380	8/22 (36%)
		leucine-rich repeat	109..132	CDD:275380	8/22 (36%)
		leucine-rich repeat	133..156	CDD:275380	5/22 (23%)
		leucine-rich repeat	157..180	CDD:275380	5/22 (23%)
		leucine-rich repeat	181..203	CDD:275380	0/21 (0%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		leucine-rich repeat	228..251	CDD:275380	8/22 (36%)
		leucine-rich repeat	252..275	CDD:275380	2/22 (9%)
CHADL	XP_054181131.1	LRRNT	33..65	CDD:214470	12/56 (21%)
		leucine-rich repeat	44..62	CDD:275380	5/40 (13%)
		leucine-rich repeat	64..87	CDD:275380	8/22 (36%)
		LRR_8	65..146	CDD:404697	24/80 (30%)
		leucine-rich repeat	88..135	CDD:275380	13/46 (28%)
		LRR	<128..>312	CDD:443914	33/206 (16%)
		leucine-rich repeat	136..159	CDD:275380	5/45 (11%)
		leucine-rich repeat	160..183	CDD:275380	7/22 (32%)
		leucine-rich repeat	184..207	CDD:275380	8/22 (36%)
		leucine-rich repeat	208..231	CDD:275380	2/22 (9%)
		leucine-rich repeat	232..255	CDD:275380	3/22 (14%)
		leucine-rich repeat	256..279	CDD:275380	2/22 (9%)
		LRRNT	395..429	CDD:214470
		leucine-rich repeat	410..426	CDD:275380
		leucine-rich repeat	427..450	CDD:275380
		LRR	<445..>677	CDD:443914
		leucine-rich repeat	451..474	CDD:275380
		leucine-rich repeat	475..498	CDD:275380
		leucine-rich repeat	499..522	CDD:275380
		leucine-rich repeat	523..546	CDD:275380
		leucine-rich repeat	547..570	CDD:275380
		leucine-rich repeat	571..594	CDD:275380
		leucine-rich repeat	595..619	CDD:275380
		leucine-rich repeat	620..644	CDD:275380
		LRRCT	675..723	CDD:214507