Protein Alignment CG1504 and CHAD

DIOPT Version :10

• Sequence 1: NP_608382.2
• Gene: CG1504 / 33028
• FlyBaseID: FBgn0031100
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_054170751.1
• Gene: CHAD / 1101
• HGNCID: 1909
• Length: 440
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 86/341 - (25%)
• Similarity: 159/341 - (46%)
• Gaps: 23/341 - (6%)

  Fly    29 SCPAECICLSQTQ-VLCNTGGLEQIPLRQLPATVENLALTKNNFPIIKPDSFAGLRALKKLSLDG 92
            :||..|.|.|..| |:|:..||::||  ::....:.|.|.:||||::..:||..:..|..|.|..
Human   103 ACPQNCHCHSDLQHVICDKVGLQKIP--KVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQH 165

  Fly    93 NNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGNAFAGTSNI 157
            ..|..:...|||||.:|..|.:.:..::::...||..|..|:.:.|.||::..:.....:...|:
Human   166 CQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNL 230

  Fly   158 KLILLTNNPLIRIDSSAFSSLTNVGHLIL-PSGIRSIEQDAFFGMDTVGLLKLAYMDLKEVAPFT 221
            .::.|.||.:..:.:.||....::..|.| .:.:.|::..|   :|.|..|...::|..:::.:.
Human   231 FILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGA---LDDVENLAKFHVDRNQLSSYP 292

  Fly   222 FRGLSNVLL---LTLQESDLGVICADAFTGLTQ-VETLQILNNKIDSIEELNFTSTAAIKHLKFF 282
            ...||.:.:   |.|..:.|..|..:||....: :|||.:.|..::...:..|.....:||:...
Human   293 SAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 357

  Fly   283 GNHVLETPDPNSIIVDGVEHLQLVSNHFPCGCHIHTLLDGPLAEGAH-NLTDFLQKNYCISPLEV 346
            .|.:.:.  |::...|.:|.|.|.:|.:.|.|.:..|.....|:.:. :.|       |.||.:.
Human   358 NNRLNQL--PSNFPFDSLETLALTNNPWKCTCQLRGLRRWLEAKASRPDAT-------CASPAKF 413

  Fly   347 NGRVMSELDIDSIGRC 362
            .|:.:.  |.|:...|
Human   414 KGQHIR--DTDAFRSC 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1504	NP_608382.2	leucine-rich repeat	61..84	CDD:275380	8/22 (36%)
		LRR_5	73..200	CDD:463839	30/127 (24%)
		leucine-rich repeat	85..108	CDD:275380	9/22 (41%)
		leucine-rich repeat	109..132	CDD:275380	5/22 (23%)
		leucine-rich repeat	133..156	CDD:275380	4/22 (18%)
		leucine-rich repeat	157..180	CDD:275380	5/22 (23%)
		leucine-rich repeat	181..203	CDD:275380	4/22 (18%)
		leucine-rich repeat	204..227	CDD:275380	4/22 (18%)
		leucine-rich repeat	228..251	CDD:275380	6/25 (24%)
		leucine-rich repeat	252..275	CDD:275380	5/22 (23%)
CHAD	XP_054170751.1	LRRNT	104..130	CDD:396168	12/27 (44%)
		LRR	131..>382	CDD:443914	61/255 (24%)
		leucine-rich repeat	134..157	CDD:275380	8/22 (36%)
		leucine-rich repeat	158..181	CDD:275380	9/22 (41%)
		leucine-rich repeat	182..205	CDD:275380	5/22 (23%)
		leucine-rich repeat	206..229	CDD:275380	4/22 (18%)
		leucine-rich repeat	230..253	CDD:275380	5/22 (23%)
		leucine-rich repeat	254..277	CDD:275380	6/25 (24%)
		leucine-rich repeat	278..301	CDD:275380	4/22 (18%)
		leucine-rich repeat	302..325	CDD:275380	6/22 (27%)
		leucine-rich repeat	327..350	CDD:275380	5/22 (23%)
		leucine-rich repeat	351..373	CDD:275380	5/23 (22%)
		LRRCT	381..428	CDD:214507	13/56 (23%)