DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1504 and LRRC17

DIOPT Version :9

Sequence 1:NP_001259742.1 Gene:CG1504 / 33028 FlyBaseID:FBgn0031100 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001026862.1 Gene:LRRC17 / 10234 HGNCID:16895 Length:441 Species:Homo sapiens


Alignment Length:347 Identity:70/347 - (20%)
Similarity:113/347 - (32%) Gaps:126/347 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 LKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAFAGLQNLSTILLSHNQIQRIEGN 149
            |..:.|..|.|..:|...|....:||.|.:|...:..:...||.||..|:|:||.||||:.:...
Human    83 LLHMLLARNKIRTLKNNMFSKFKKLKSLDLQQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEE 147

  Fly   150 AFAGTSNIKLILLTNNP------------LIRIDSSAFSSLTNVGHLILP-----SGIRSIEQDA 197
            .|..|..:..:.|.:||            :::|..:  .:|.|......|     ..:|.|:.:.
Human   148 VFIYTPLLSYLRLYDNPWHCTCEIETLISMLQIPRN--RNLGNYAKCESPQEQKNKKLRQIKSEQ 210

  Fly   198 F-----------------------------------FGMDTVGL------------------LKL 209
            .                                   |.:.|:..                  |.|
Human   211 LCNEEEKEQLDPKPQVSGRPPVIKPEVDSTFCHN
YVFPIQTLDCKRKELKKVPNNIPPDIVKLDL 275

  Fly   210 AYMDLKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQILNNKIDS-----IEELN 269
            :|..:.::.|..|..:..:..|.|..:.:..|...||.|||.:|.|.:.||.:.:     :|:|.
Human   276 SYNKINQLRPKEFEDVHELKKLNLSSNGIEFIDPAAFLGLTHLEELDLSNNSLQNFDYGVLEDLY 340

  Fly   270 FTSTAAIKHLKFFGNHVLETPDPNSIIVDGVEHLQLVSNHFPCGCHIHTLLDGPLAEGAHNLTDF 334
            |        ||.                     |.|..|.:.|..:||.|.            .:
Human   341 F--------LKL---------------------LWLRDNPWRCDYNIHYLY------------YW 364

  Fly   335 LQKNY--------CISPLEVNG 348
            |:.:|        |.:|.|..|
Human   365 LKHHYNVHFNGLECKTPEEYKG 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1504NP_001259742.1 leucine-rich repeat 61..84 CDD:275380
LRR_5 73..200 CDD:404228 33/166 (20%)
leucine-rich repeat 85..108 CDD:275380 6/22 (27%)
leucine-rich repeat 109..132 CDD:275380 8/22 (36%)
leucine-rich repeat 133..156 CDD:275380 10/22 (45%)
leucine-rich repeat 157..180 CDD:275380 5/34 (15%)
leucine-rich repeat 181..203 CDD:275380 4/61 (7%)
leucine-rich repeat 204..227 CDD:275380 5/40 (13%)
leucine-rich repeat 228..251 CDD:275380 7/22 (32%)
leucine-rich repeat 252..275 CDD:275380 7/27 (26%)
LRRC17NP_001026862.1 leucine-rich repeat 63..81 CDD:275380
LRR 1 82..103 6/19 (32%)
LRR_8 84..141 CDD:290566 19/56 (34%)
leucine-rich repeat 84..106 CDD:275380 5/21 (24%)
LRR_4 105..146 CDD:289563 16/40 (40%)
LRR 2 106..127 6/20 (30%)
leucine-rich repeat 107..130 CDD:275380 8/22 (36%)
LRR 3 130..151 9/20 (45%)
leucine-rich repeat 131..154 CDD:275380 10/22 (45%)
leucine-rich repeat 155..244 CDD:275380 9/90 (10%)
leucine-rich repeat 249..269 CDD:275380 1/19 (5%)
LRR_RI <267..>351 CDD:238064 24/112 (21%)
LRR 4 269..290 5/20 (25%)
leucine-rich repeat 270..293 CDD:275380 5/22 (23%)
LRR_8 272..328 CDD:290566 17/55 (31%)
LRR 5 293..314 5/20 (25%)
LRR_4 294..332 CDD:289563 12/37 (32%)
leucine-rich repeat 294..317 CDD:275380 7/22 (32%)
LRR 6 317..340 5/22 (23%)
leucine-rich repeat 318..341 CDD:275380 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D282791at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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