DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1504 and Islr2

DIOPT Version :9

Sequence 1:NP_001259742.1 Gene:CG1504 / 33028 FlyBaseID:FBgn0031100 Length:425 Species:Drosophila melanogaster
Sequence 2:XP_003750572.2 Gene:Islr2 / 100910729 RGDID:6497037 Length:746 Species:Rattus norvegicus


Alignment Length:336 Identity:65/336 - (19%)
Similarity:116/336 - (34%) Gaps:136/336 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MCNSWLVLIIALSVVVCLWNSQQTETSKSCPAECICLSQTQ---VLCNTGGLEQIPLRQLPATVE 62
            :|.:|.:|.:|                ::||..|.|:.:..   ..|....|.::| ..|||.|.
  Rat     8 LCLAWALLGVA----------------RACPEPCACVDKYAHQFADCAYKELREVP-EGLPANVT 55

  Fly    63 NLALTKNNFPIIKPDSFAGLRALKKLSLDGNNITRIKQFAFRGLPRLKELSIQYTPLQMVAQFAF 127
            .|:|:.|...:::                            ||                    ||
  Rat    56 TLSLSANKITVLR----------------------------RG--------------------AF 72

  Fly   128 AGLQNLSTILLSHNQIQRIEGNAFAGTSNIKLILLTNNPLIRIDSSAFSSLTNVGHLILPSGIRS 192
            ..:..::::.|:|::::.:|..|.|..|.:|.:.|::|   .|.:..:|.|              
  Rat    73 VNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHN---LISNFPWSDL-------------- 120

  Fly   193 IEQDAFFGMDTVGLLKLAYMDLKEVAPFTFRGLSNVLLLTLQESDLGVICADAFTGLTQVETLQI 257
                                          |.||.:.||.:..:.||.:..||...|..:.:|:|
  Rat   121 ------------------------------RNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRI 155

  Fly   258 LNNKIDSIEELNFTSTAAIKHLKFFGN--HV---------------LETPDPNSIIVDGVEHLQL 305
            .||::.::|...|.:.:|:.||:.:.|  |.               :..|:|:||.......||.
  Rat   156 NNNRLRTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQG 220

  Fly   306 VSNH----FPC 312
            |..|    .||
  Rat   221 VPVHRLPALPC 231

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1504NP_001259742.1 leucine-rich repeat 61..84 CDD:275380 4/22 (18%)
LRR_5 73..200 CDD:404228 16/126 (13%)
leucine-rich repeat 85..108 CDD:275380 2/22 (9%)
leucine-rich repeat 109..132 CDD:275380 2/22 (9%)
leucine-rich repeat 133..156 CDD:275380 5/22 (23%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
leucine-rich repeat 181..203 CDD:275380 0/21 (0%)
leucine-rich repeat 204..227 CDD:275380 2/22 (9%)
leucine-rich repeat 228..251 CDD:275380 7/22 (32%)
leucine-rich repeat 252..275 CDD:275380 6/22 (27%)
Islr2XP_003750572.2 leucine-rich repeat 37..53 CDD:275380 5/16 (31%)
leucine-rich repeat 54..77 CDD:275380 8/70 (11%)
leucine-rich repeat 78..101 CDD:275380 5/22 (23%)
LRR_8 100..160 CDD:404697 21/106 (20%)
leucine-rich repeat 102..125 CDD:275380 8/69 (12%)
leucine-rich repeat 126..149 CDD:275380 7/22 (32%)
leucine-rich repeat 150..173 CDD:275380 6/22 (27%)
PCC 155..>229 CDD:188093 18/73 (25%)
Ig 249..374 CDD:416386
Ig strand B 257..264 CDD:409353
Ig strand C 270..278 CDD:409353
Ig strand C' 280..287 CDD:409353
Ig strand D 333..337 CDD:409353
Ig strand E 340..345 CDD:409353
Ig strand F 353..361 CDD:409353
Ig strand G 364..374 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D282791at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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