DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Inx7 and Inx5

DIOPT Version :9

Sequence 1:	NP_788872.1	Gene:	Inx7 / 33027	FlyBaseID:	FBgn0027106	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_573353.2	Gene:	Inx5 / 32901	FlyBaseID:	FBgn0030989	Length:	419	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	117/428 - (27%)
Similarity:	186/428 - (43%)	Gaps:	88/428 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FSSVR---QYLKFDLTRVVIDNIVFKLHYRWTFVILLVATLLITSRQYIGEHIQCLSDGVVSPVI 66
            ||:|:   :||:|...|:.  :.||.:|.|.|.||||..:||:::|||.|:.|||:|:......|
  Fly     2 FSAVKPLSKYLQFKSIRIY--DSVFTIHSRCTVVILLTCSLLLSARQYFGDPIQCISEEKNIEYI 64

  Fly    67 NTFCFFTPTFTV----VRDQNQTAYRPGSEPPGIGAF-------DPE-----------KDTIKRH 109
            .::|:...|:.:    ..||.|....|..|.....||       .|:           :.:::|.
  Fly    65 QSYCWTMGTYILKLDDFGDQEQALVSPNQEVSYNSAFFSSATTNAPQSSSRVRTRPHFRSSLRRI 129

  Fly   110 A------------------------------YYQWVPFVLFFQALCFYIPHALWKSWEGGRIKAL 144
            .                              |||||..:|.||:..||.|..|||.|||.|:|.|
  Fly   130 GEYNEAYARSLSIAEGVGPEIRGQTERQYLRYYQWVIILLLFQSFVFYFPSCLWKVWEGRRLKQL 194

  Fly   145 VFGLRMVGLTRYLKNDSLRIGKLNIPSMAEAEERVKDIRRTMIDRMRLNQSWGAHLVFAEVLNLI 209
            ...:....|:....|..||:                .::....|...::..:.|..||.||||.:
  Fly   195 CSEVGDALLSEETYNTRLRM----------------LVKYFTTDYEDMHFCYMAKYVFCEVLNFL 243

  Fly   210 NLLLQITWTNRFLGG------QFLTLGPHALKNRWSDELSVLDLVFPKITKCKFHKFGDSGSIQM 268
            ..::.|.....||.|      :.|...|....:||:   .|...|||||.||:..|||.||:..:
  Fly   244 ISVVNIIVLEVFLNGFWSKYLRALATIPFYDWDRWN---RVSSSVFPKIAKCEVLKFGGSGTANV 305

  Fly   269 HDALCVMALNIMNEKIYIILWFWYAFLLIVTVLGLLWRILTLCF-YRNVTFTRWSLYWAKPGQLD 332
            .|.||::.|||:||||::.||.|:..:.:::.|.||.|:..:|. |......|..|.:     :.
  Fly   306 MDNLCILPLNILNEKIFVFLWAWFLLMALMSGLNLLCRLAMICSRYLREQMIRSQLRF-----MT 365

  Fly   333 ENELLAVIDKCNFSNWMFLFFLRSNLSEFLFKKVIYHL 370
            :..:...:......:|..:..:..|::..||:.::..|
  Fly   366 KRHVKRALRDLTIGDWFLMMKVSVNVNPMLFRDLMQEL 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Inx7	NP_788872.1	Innexin	22..374	CDD:279248	110/408 (27%)
Inx5	NP_573353.2	Innexin	21..405	CDD:279248	110/407 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I3133
eggNOG	1	0.900	-	-		E1_2BWHM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3152
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D323554at33208
OrthoFinder	1	1.000	-	-		FOG0003274
OrthoInspector	1	1.000	-	-		mtm4755
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11893
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X282
	9	8.970