DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17065 and amdhd2

DIOPT Version :9

Sequence 1:	NP_001162805.1	Gene:	CG17065 / 33026	FlyBaseID:	FBgn0031099	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001120283.1	Gene:	amdhd2 / 100145339	XenbaseID:	XB-GENE-976354	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	414	Identity:	232/414 - (56%)
Similarity:	310/414 - (74%)	Gaps:	16/414 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PEQKILASSQRLLQFTNCRLVRDHRIIHDDLWVRDGRIVNPEPVFFDERTKAHCRIDCGGAIIAP 79
            |..|.: |...::||.|||::|||.:..:|||||.|:::|||.:||||:..|..::||.|.||||
Frog     2 PSNKSV-SDAPIVQFRNCRILRDHTLQREDLWVRQGKVLNPEKLFFDEKGYADMQVDCRGLIIAP 65

  Fly    80 GYIDLQINGGYGVDFSYDTETIEEGVATVARGLVKSGVTSFCPTLVTSPSDSYHTILPRIPAE-- 142
            |:||.|:|||:|||||:::..::.|:..|::.::..||||||||||||||..||.:||:|...
Frog    66 GFIDTQLNGGFGVDFSFESNDVKTGICVVSKNILSHGVTSFCPTLVTSPSSVYHKVLPQISVRDG 130

  Fly   143 VPKGAGILGIHAEGPFINPQKKGAHPEHCIQTIDKRDHSNVTFRLPRLKGLSTLKETYGSLERIK 207
            .|:|||:||:|.|||:|:.:|||||||||:::..:|             |.:.|.:|||:||.:.
Frog   131 GPEGAGVLGVHLEGPYISREKKGAHPEHCLRSFSER-------------GFADLLDTYGTLENVS 182

  Fly   208 IITLAPEKVTDPEVIGQLVERGITVALGHSMASLSDGERAVQQGATLITHLFNAMLPFHHRDPGL 272
            ::|||||.....|||.:||:|||.|:||||:|:||..|.||..||:.|||||||||||||||||:
Frog   183 LVTLAPEMERSTEVIKELVQRGICVSLGHSVANLSQAEDAVSHGASFITHLFNAMLPFHHRDPGI 247

  Fly   273 VGLLASDAVPHGRTVYFGIISDGVHTHPAALRIAYRTHPQGLILVTDAISALGLEEGVHHIGQLP 337
            ||||.||.:|.|:|||:|:|:||:||:|||||||:|.||:||:||||||:|:||..|.|.:||..
Frog   248 VGLLTSDQIPKGKTVYYGMIADGIHTNPAALRIAHRAHPKGLVLVTDAITAMGLGPGKHTLGQQE 312

  Fly   338 LQVKQGKAFIAGTETLCGSIAPMDECVRIFQKATDCSVVYAIEAATLHPAQCLKIEKQKGTLDFG 402
            :.::...|::|||.||.||||.||.|||.|.:||.|:|..|:|||:|||||.|.|:..|||||||
Frog   313 ILIEGLNAYVAGTHTLAGSIATMDMCVRHFHEATGCTVEEALEAASLHPAQVLGIQDHKGTLDFG 377

  Fly   403 SDADFVLLDDQLRVLSTWIAGVCV 426
            :|||||||||.|.|.:|:|||..|
Frog   378 ADADFVLLDDSLHVKATYIAGKLV 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17065	NP_001162805.1	NagA	27..423	CDD:238434	226/397 (57%)
CG17065	NP_001162805.1	HutI	38..431	CDD:224149	222/391 (57%)
amdhd2	NP_001120283.1	NagA	13..398	CDD:238434	226/397 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	427	1.000	Domainoid score	I602
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9311
Inparanoid	1	1.050	489	1.000	Inparanoid score	I1395
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1066877at2759
OrthoFinder	1	1.000	-	-		FOG0006638
OrthoInspector	1	1.000	-	-		oto103310
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4676
SonicParanoid	1	1.000	-	-		X4269
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.090