Protein Alignment Rab10 and Rab35

DIOPT Version :10

• Sequence 1: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Sequence 2: NP_937806.1
• Gene: Rab35 / 77407
• MGIID: 1924657
• Length: 201
• Species: Mus musculus
• Alignment Length: 204
• Identity: 92/204 - (45%)
• Similarity: 144/204 - (70%)
• Gaps: 9/204 - (4%)

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.||.|||||:||||||||:.:|.||:|:.|:.::|:|||:||||:|||:.|:|:||||||||||
Mouse     3 RDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQ 67

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            |||.|||::||||..|:::|||:|:.:||.|:.:||..|:::. :||.::::|||.|..:::||.
Mouse    68 ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPERKVVE 131

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAIL----DKTSGRESAENQERVIIDRRNQE 194
            .|.....|.:.||:..|||||.|:|:|..|..:.|.:|    |..:.::..:..:.|.:.:.::.
Mouse   132 TEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKR 196

  Fly   195 KAPGYSKCC 203
            |    .:||
Mouse   197 K----KRCC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	86/169 (51%)
Rab35	NP_937806.1	Rab35	3..201	CDD:133310	90/202 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q15286	30..42		4/11 (36%)
		Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q15286	64..80		12/15 (80%)