DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and Rab35

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_937806.1	Gene:	Rab35 / 77407	MGIID:	1924657	Length:	201	Species:	Mus musculus

Alignment Length:	204	Identity:	92/204 - (45%)
Similarity:	144/204 - (70%)	Gaps:	9/204 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.||.|||||:||||||||:.:|.||:|:.|:.::|:|||:||||:|||:.|:|:||||||||||
Mouse     3 RDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQ 67

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            |||.|||::||||..|:::|||:|:.:||.|:.:||..|:::. :||.::::|||.|..:::||.
Mouse    68 ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPERKVVE 131

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAIL----DKTSGRESAENQERVIIDRRNQE 194
            .|.....|.:.||:..|||||.|:|:|..|..:.|.:|    |..:.::..:..:.|.:.:.::.
Mouse   132 TEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKR 196

  Fly   195 KAPGYSKCC 203
            |    .:||
Mouse   197 K----KRCC 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	86/169 (51%)
Rab35	NP_937806.1	Rab35	3..201	CDD:133310	90/202 (45%)
Rab35	NP_937806.1	Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910